Recombinant Human MERTK, GST-tagged, Active
Cat.No. : | MERTK-258H |
Product Overview : | Recombinant human c-MER (578-872) was expressed by baculovirus inSf9 insect cellsusing an N-terminal GST tag. |
- Specification
- Gene Information
- Related Products
Cat. No. : | MERTK-258H |
Description : | c-MER is a tyrosine kinase and a member of the MER/AXL/TYRO3 receptor kinase family. The c-MER gene encodes a transmembrane protein with two fibronectin type-III domains, two Ig-like C2-type domains, and one tyrosine kinase domain. Functional knockout of c-MER in mice shows the mice to have macrophages deficient in the clearance of apoptotic thymocytes thereby demonstrating the critical role for c-MER in the engulfment and efficient clearance of apoptotic cells. Defects in c-MER have been associated with retinitis pigmentosa, a phenotype that can be reversed by replacement of the c-MER gene product. |
Source : | Sf9 insect cells using baculovirus. |
Sequence : | 578-872. |
Applications : | Kinase Assay, Western Blot. |
Storage And Stability : | Store product at -70°C. For optimal storage, aliquot target into smaller quantities after centrifugation and store at recommended temperature. For most favorable performance, avoid repeated handling and multiple freeze/thaw cycles. |
Gene Name : | MERTK c-mer proto-oncogene tyrosine kinase [ Homo sapiens ] |
Synonyms : | MERTK; c-mer proto-oncogene tyrosine kinase; MER; RP38; c-mer; MGC133349; MER receptor tyrosine kinase; STK kinase; EC 2.7.10.1; Receptor tyrosine kinase MerTK; Proto-oncogene tyrosine-protein kinase MER |
Gene ID : | 10461 |
mRNA Refseq : | NM_006343 |
Protein Refseq : | NP_006334 |
MIM : | 604705 |
UniProt ID : | Q12866 |
Chromosome Location : | 2q14.1 |
Pathway : | Hemostasis; Signaling in Immune system |
Function : | ATP binding; nucleotide binding; protein binding; receptor activity; transferase activity; transmembrane receptor protein tyrosine kinase activity |
Products Types
◆ Recombinant Protein | ||
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MERTK-950H | Recombinant Human MERTK Protein, MYC/DDK-tagged | +Inquiry |
Mertk-001D | Recombinant Dog MERTK protein, GST-tagged | +Inquiry |
Mertk-4035M | Recombinant Mouse Mertk Protein, Myc/DDK-tagged | +Inquiry |
◆ Lysates | ||
MERTK-413MCL | Recombinant Mouse MERTK cell lysate | +Inquiry |
MERTK-2888HCL | Recombinant Human MERTK cell lysate | +Inquiry |
MERTK-1816MCL | Recombinant Mouse MERTK cell lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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