Human MERTK Knockdown Cell Lysate

• Cat.No.: MERTK-504HKCL
• Product Overview: WB-validated MERTK Knockdown HT-1080 Cell Lysate

Specification

• Species: Human
• Source: HT-1080
• Tag: Non
• Description: This gene is a member of the MER/AXL/TYRO3 receptor kinase family and encodes a transmembrane protein with two fibronectin type-III domains, two Ig-like C2-type (immunoglobulin-like) domains, and one tyrosine kinase domain. Mutations in this gene have been associated with disruption of the retinal pigment epithelium (RPE) phagocytosis pathway and onset of autosomal recessive retinitis pigmentosa (RP).
• Form: Cell-Tissue Lysis buffer
• Molecular Mass: 110 kDa
• Notes: Instruction of use: This knockdown cell lysate should be paired with wild-type HT-1080 cell lysate for use. For Western blotting, we recommend running wild-type and knockdown lysates on the same gel, and loading each well with equal volume and equal amount of total proteins.
• Storage: Store at -20 centigrade for two years.
• Concentration: Lot-specific
• Shipping: Blue Ice
• Components: 1 vial of 100 μg WT HT-1080 cell lysate 1 vial of 100 μg MERTK KD HT-1080 cell lysate
• Protein Families: Druggable Genome, Protein Kinase, Transmembrane
• Lysate QC: RT-qPCR; Western Blotting (WB)

Gene Information

• Gene Name: MERTK c-mer proto-oncogene tyrosine kinase [ Homo sapiens (human) ]
• Official Symbol: MERTK
• Synonyms: MERTK; c-mer proto-oncogene tyrosine kinase; tyrosine-protein kinase Mer; mer; RP38; STK kinase; proto-oncogene c-Mer; MER receptor tyrosine kinase; receptor tyrosine kinase MerTK; MER; c-mer; MGC133349
• Gene ID: 10461
• mRNA Refseq: NM_006343
• Protein Refseq: NP_006334
• MIM: 604705
• UniProt ID: Q12866