Recombinant Human Protein Kinase C, Theta, GST-tagged, Active
Cat.No. : | PRKCQ-408H |
Product Overview : | Recombinant full-length human PRKCQ was expressed bybaculovirusinSf9 insect cellsusing an N-terminal GST tag. MW=110 kDa. |
- Specification
- Gene Information
- Related Products
Cat. No. : | PRKCQ-408H |
Description : | Protein Kinase C, theta (PKCθ) is important component in the intracellular signaling cascade. Recent studies have suggested that local accumulation of fat metabolites inside skeletal muscle may activate a serine kinase cascade involving PKC-theta leading to defects in insulin signaling and glucose transport in skeletal muscle. Insulin resistance plays a primary role in the development of type 2 diabetes and may be related to alterations in fat metabolism. PKC-theta is a crucial component mediating fat-induced insulin resistance in skeletal muscle and is a potential therapeutic target for the treatment of type 2 diabetes. |
Source : | Sf9 insect cells using baculovirus. |
Sequence : | Full-length. |
Applications : | Kinase Assay, Western Blot. |
Storage And Stability : | Store product at –70oC. For optimal storage, aliquot target into smaller quantities after centrifugation and store at recommended temperature. For most favorable performance, avoid repeated handling and multiple freeze/thaw cycles. |
Gene Name : | PRKCQ protein kinase C, theta [ Homo sapiens ] |
Synonyms : | PRKCQ; protein kinase C, theta; PRKCT; MGC126514; MGC141919; nPKC-theta; Protein kinase C theta type; EC 2.7.11.13 |
Gene ID : | 5588 |
mRNA Refseq : | NM_006257 |
Protein Refseq : | NP_006248 |
MIM : | 600448 |
UniProt ID : | Q04759 |
Chromosome Location : | 10p15 |
Pathway : | Adipocytokine signaling pathway; T cell receptor signaling pathway; Tight junction; Vascular smooth muscle contraction; Apoptosis; Signaling in Immune system |
Function : | ATP binding; calcium ion binding; nucleotide binding; protein kinase C activity; transferase activity; zinc ion binding |
Products Types
◆ Recombinant Protein | ||
PRKCQ-3425R | Recombinant Rhesus Macaque PRKCQ Protein, His (Fc)-Avi-tagged | +Inquiry |
PRKCQ-30178TH | Recombinant Human PRKCQ | +Inquiry |
PRKCQ-3942H | Recombinant Human PRKCQ protein, His-tagged | +Inquiry |
PRKCQ-5995H | Recombinant Human PRKCQ Protein (Phe380-Phe634), N-GST tagged | +Inquiry |
PRKCQ-3607R | Recombinant Rhesus monkey PRKCQ Protein, His-tagged | +Inquiry |
◆ Lysates | ||
PRKCQ-1416HCL | Recombinant Human PRKCQ cell lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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