"STK3" Related Products


Recombinant Human STK3, GST-tagged, Active

Cat. No. : STK3-437H
Product Overview : Recombinant full-length human STK3 was expressed by baculovirus inSf9insect cells using a N-terminal GST tag. MW = 87 kDa.
Description : STK3, also known as MST2, encodes a protein of 491-amino acid which contains an N-terminal catalytic domain characteristic of STKs. STK3 and STK4 share 94% amino acid identity in the catalytic domain and 78% identity overall. RAF1 has been shown to counteract apoptosis by suppressing the activation of mammalian sterile 20-like kinase (MST2). STK3 is a kinase that is activated by the proapoptotic agents straurosporine and FAS ligand. STK3 activation presumably allows cells to resist unfavorable environmental conditions.
Source : Sf9 insect cells using baculovirus.
Sequence : Full-length.
Applications : Kinase Assay, Western Blot.
Storage And Stability : Store product at -70℃. For optimal storage, aliquot target into smaller quantities after centrifugation and store at recommended temperature. For most favorable performance, avoid repeated handling and multiple freeze/thaw cycles.
Gene Name : STK3 serine/threonine kinase 3 (STE20 homolog, yeast) [ Homo sapiens ]
Synonyms : STK3; serine/threonine kinase 3 (STE20 homolog, yeast); KRS1; MST2; FLJ90748; serine/threonine kinase 3; serine/threonine kinase 3 (Ste20, yeast homolog); EC; MST-2; Mammalian STE20-like protein kinase 2; STE20-like kinase MST2; Serine/threonine-protein kinase Krs-1; Serine/threonine-protein kinase 3
Gene ID : 6788
mRNA Refseq : NM_006281
Protein Refseq : NP_006272
MIM : 605030
UniProt ID : Q13188
Chromosome Location : 8q22.2
Pathway : MAPK signaling pathway
Function : ATP binding; magnesium ion binding; nucleotide binding; protein dimerization activity; protein serine/threonine kinase activity; transferase activity

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