"MTHFD2" Related Products

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Recombinant Human MTHFD2, T7-tagged

Cat. No. : MTHFD2-393H
Product Overview : Recombinant Human MTHFD2 was expressed inE.Coliusing an N-terminal T7 tag. MW=39.56 kDa.
Description : This is a nuclear-encoded mitochondrial bifunctional enzyme with methylenetetrahydrofolate dehydrogenase and methenyltetrahydrofolate cyclohydrolase activities. The enzyme functions as a homodimer and is unique in its absolute requirement for magnesium and inorganic phosphate. Formation of the enzyme-magnesium complex allows binding of NAD.
Source : E.Coli.
Sequence : 1-344.
Purity : ~95%.
Specific Activity : n/aH.
Applications : This recombinant protein can be used for WB, ELISA, MS and neutralization assays.
Buffer : 10 mM Tris, pH 8.0, 0.1% Triton X-100, 0.002% NaN3.
Storage : Store at -70?C. As with any protein, exposing MTHFD2 recombinant protein to repeated freeze/thaw cycles is not recommended. When working with proteins care should be taken to keep recombinant protein at a cool and stable temperature.
SDS-PAGE : SDS PAGE Analysis of MTHFD2 Recombinant Protein. 4-20% SDS gradient gel. Coomassie blue staining.MTHFD2, T7-tagged(Human),Recombinant Human MTHFD2, T7-tagged
Gene Name : MTHFD2 methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 2, methenyltetrahydrofolate cyclohydrolase [ Homo sapiens ]
Synonyms : MTHFD2; methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 2, methenyltetrahydrofolate cyclohydrolase; NMDMC; methylenetetrahydrofolate dehydrogenase 2; NAD-dependent methylene tetrahydrofolate dehydrogenase cyclohydrolase methylene tetrahydrofolate dehydrogenase (NAD+ dependent), methenyltetrahydrofolate cyclohydrolase; EC 1.5.1.15
Gene ID : 10797
mRNA Refseq : NM_006636
Protein Refseq : NP_006627
MIM : 604887
UniProt ID : P13995
Chromosome Location : 2p13.1
Pathway : Glyoxylate and dicarboxylate metabolism; Metabolic pathways; One carbon pool by folate
Function : binding; hydrolase activity; methenyltetrahydrofolate cyclohydrolase activity; methylenetetrahydrofolate dehydrogenase (NADP+) activity; oxidoreductase activity; phosphate binding

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