Recombinant Human ALCAM

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Recombinant Human ALCAM

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Cat.No. : ALCAM-27218TH
Product Overview : Recombinant fragment corresponding to amino acids 28-137 of Human CD166, with a proprietary tag; predicted MWt 37.73kDa inclusive of tag;
Description : This gene encodes activated leukocyte cell adhesion molecule (ALCAM), also known as CD166 (cluster of differentiation 166), which is a member of a subfamily of immunoglobulin receptors with five immunoglobulin-like domains (VVC2C2C2) in the extracellular domain. This protein binds to T-cell differentiation antigene CD6, and is implicated in the processes of cell adhesion and migration. Multiple alternatively spliced transcript variants encoding different isoforms have been found.
Protein length : 110 amino acids
Molecular Weight : 37.730kDa inclusive of tags
Source : Wheat germ
Tissue specificity : Spleen, placenta, liver, and weakly in liver. Expressed by activated T-cells, B-cells, monocytes and thymic epithelial cells. Expressed by neurons in the brain. Restricted expression in tumor cell lines. Preferentially expressed in highly metastasizing me
Form : Liquid
Purity : Proprietary Purification
Storage buffer : pH: 8.00Constituents:0.31% Glutathione, 0.79% Tris HCl
Storage : Shipped on dry ice. Upon delivery aliquot and store at -80oC. Avoid freeze / thaw cycles.
Sequences of amino acids : WYTVNSAYGDTIIIP CRLDVPQNLMFGKWK YEKPDGSPVFIAFRS STKKSVQYDDVPEYK DRLNLSENYTLSISN ARISDEKRFVCMLVT EDNVFEAPTIVKVFK QPSKP
Sequence Similarities : Contains 3 Ig-like C2-type (immunoglobulin-like) domains.Contains 2 Ig-like V-type (immunoglobulin-like) domains.
Gene Name : ALCAM activated leukocyte cell adhesion molecule [ Homo sapiens ]
Official Symbol : ALCAM
Synonyms : ALCAM; activated leukocyte cell adhesion molecule; activated leucocyte cell adhesion molecule; CD166 antigen; CD166; MEMD;
Gene ID : 214
mRNA Refseq : NM_001243280
Protein Refseq : NP_001230209
MIM : 601662
Uniprot ID : Q13740
Chromosome Location : 3q13.1
Pathway : Axon guidance, organism-specific biosystem; Cell adhesion molecules (CAMs), organism-specific biosystem; Cell adhesion molecules (CAMs), conserved biosystem; Developmental Biology, organism-specific biosystem; L1CAM interactions, organism-specific biosystem;
Function : receptor binding;

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