Recombinant Human CCL22, His-tagged
Cat.No. : | CCL22-29753TH |
Product Overview : | Recombinant full length human MDC fused to His tag at N-terminus; amino acids 25-93 , 10.3kDa. |
- Specification
- Gene Information
- Related Products
Description : | This gene is one of several Cys-Cys (CC) cytokine genes clustered on the q arm of chromosome 16. Cytokines are a family of secreted proteins involved in immunoregulatory and inflammatory processes. The CC cytokines are proteins characterized by two adjacent cysteines. The cytokine encoded by this gene displays chemotactic activity for monocytes, dendritic cells, natural killer cells and for chronically activated T lymphocytes. It also displays a mild activity for primary activated T lymphocytes and has no chemoattractant activity for neutrophils, eosinophils and resting T lymphocytes.The product of this gene binds to chemokine receptor CCR4. This chemokine may play a role in the trafficking of activated T lymphocytes to inflammatory sites and other aspects of activated T lymphocyte physiology. |
Conjugation : | HIS |
Source : | E. coli |
Tissue specificity : | Highly expressed in macrophage and in monocyte-derived dendritic cells, and thymus. Also found in lymph node, appendix, activated monocytes, resting and activated macrophages. Lower expression in lung and spleen. Very weak expression in small intestine. I |
Form : | Liquid |
Purity : | >95% by SDS-PAGE |
Storage buffer : | Preservative: NoneConstituents: 10% Glycerol, PBS, pH 7.4 |
Storage : | Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles. |
Sequences of amino acids : | MGSSHHHHHH SSGLVPRGSH MGPYGANMED SVCCRDYVRY RLPLRVVKHF YWTSDSCPRP GVVLLTFRDK EICADPRVPW VKMILNKLSQ |
Sequence Similarities : | Belongs to the intercrine beta (chemokine CC) family. |
Gene Name : | CCL22 chemokine (C-C motif) ligand 22 [ Homo sapiens ] |
Official Symbol : | CCL22 |
Synonyms : | CCL22; chemokine (C-C motif) ligand 22; SCYA22, small inducible cytokine subfamily A (Cys Cys), member 22; C-C motif chemokine 22; A 152E5.1; ABCD 1; DC/B CK; MDC; MGC34554; STCP 1; |
Gene ID : | 6367 |
mRNA Refseq : | NM_002990 |
Protein Refseq : | NP_002981 |
MIM : | 602957 |
Uniprot ID : | O00626 |
Chromosome Location : | 16q13 |
Pathway : | Chemokine receptors bind chemokines, organism-specific biosystem; Chemokine signaling pathway, organism-specific biosystem; Chemokine signaling pathway, conserved biosystem; Class A/1 (Rhodopsin-like receptors), organism-specific biosystem; Cytokine-cytokine receptor interaction, organism-specific biosystem; |
Function : | chemokine activity; |
Products Types
◆ Recombinant Protein | ||
CCL22-1108P | Recombinant Pig CCL22 Protein, His-tagged | +Inquiry |
Ccl22-131M | Active Recombinant Mouse Ccl22 Protein | +Inquiry |
CCL22-2884M | Recombinant Mouse CCL22 Protein | +Inquiry |
Ccl22-042C | Active Recombinant Mouse Ccl22 Protein (68 aa) | +Inquiry |
CCL22-081C | Active Recombinant Human CCL22 Protein (69 aa) | +Inquiry |
◆ Lysates | ||
CCL22-7728HCL | Recombinant Human CCL22 293 Cell Lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
Inquiry
0
Inquiry Basket