Recombinant Human CD4
Cat.No. : | CD4-27808TH |
Product Overview : | Recombinant fragment, corresponding to amino acids 26-226 of Human CD4 |
- Specification
- Gene Information
- Related Products
Description : | This gene encodes a membrane glycoprotein of T lymphocytes that interacts with major histocompatibility complex class II antigenes and is also a receptor for the human immunodeficiency virus. This gene is expressed not only in T lymphocytes, but also in B cells, macrophages, and granulocytes. It is also expressed in specific regions of the brain. The protein functions to initiate or augment the early phase of T-cell activation, and may function as an important mediator of indirect neuronal damage in infectious and immune-mediated diseases of the central nervous system. Multiple alternatively spliced transcript variants encoding different isoforms have been identified in this gene. |
Source : | E. coli |
Form : | Liquid |
Storage buffer : | Preservative: NoneConstituents: 20% Glycerol, 50mM Tris acetate, 1mM EDTA, pH 7.5 |
Storage : | Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles. |
Sequence Similarities : | Contains 3 Ig-like C2-type (immunoglobulin-like) domains.Contains 1 Ig-like V-type (immunoglobulin-like) domain. |
Gene Name : | CD4 CD4 molecule [ Homo sapiens ] |
Official Symbol : | CD4 |
Synonyms : | CD4; CD4 molecule; CD4 antigen (p55); T-cell surface glycoprotein CD4; |
Gene ID : | 920 |
mRNA Refseq : | NM_000616 |
Protein Refseq : | NP_000607 |
MIM : | 186940 |
Uniprot ID : | P01730 |
Chromosome Location : | 12pter-p12 |
Pathway : | Adaptive Immune System, organism-specific biosystem; Antigen processing and presentation, organism-specific biosystem; Antigen processing and presentation, conserved biosystem; Arf1 pathway, organism-specific biosystem; Binding and entry of HIV virion, organism-specific biosystem; |
Function : | MHC class II protein binding; coreceptor activity; enzyme binding; extracellular matrix structural constituent; glycoprotein binding; |
Products Types
◆ Recombinant Protein | ||
CD4-313H | Active Recombinant Human CD4 Protein (Lys 26 - Pro 396), His & Avi-tagged, Biotinylated | +Inquiry |
Cd4-841M | Recombinant Mouse Cd4 Protein, MYC/DDK-tagged | +Inquiry |
CD4-23H | Recombinant Human CD4 Protein, Fc & Avi-tagged | +Inquiry |
CD4-0807H | Recombinant Human CD4 Protein, GST-Tagged | +Inquiry |
CD4-172H | Recombinant Human CD4 Protein, C-His-tagged | +Inquiry |
◆ Lysates | ||
CD4-1865FCL | Recombinant Ferret CD4 cell lysate | +Inquiry |
CD4-947CCL | Recombinant Cynomolgus CD4 cell lysate | +Inquiry |
CD4-2580MCL | Recombinant Mouse CD4 cell lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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