Recombinant Human DEFA6

• Cat.No.: DEFA6-26996TH
• Product Overview: Recombinant full length Human DEFA6 , with N terminal proprietary tag; Predicted MW 37.07kDa.

Specification

• Description: Defensins are a family of microbicidal and cytotoxic peptides thought to be involved in host defense. They are abundant in the granules of neutrophils and also found in the epithelia of mucosal surfaces such as those of the intestine, respiratory tract, urinary tract, and vagina. Members of the defensin family are highly similar in protein sequence and distinguished by a conserved cysteine motif. Several alpha defensin genes appear to be clustered on chromosome 8. The protein encoded by this gene, defensin, alpha 6, is highly expressed in the secretory granules of Paneth cells of the small intestine, and likely plays a role in host defense of human bowel.
• Protein length: 100 amino acids
• Molecular Weight: 37.070kDa inclusive of tags
• Source: Wheat germ
• Tissue specificity: Paneth cells of the small intestine.
• Form: Liquid
• Purity: Proprietary Purification
• Storage buffer: pH: 8.00Constituents:0.3% Glutathione, 0.79% Tris HCl
• Storage: Shipped on dry ice. Upon delivery aliquot and store at -80oC. Avoid freeze / thaw cycles.
• Sequences of amino acids: MRTLTILTAVLLVALQAKAEPLQAE DDPLQAKAYEADAQEQRGANDQDFA VSFAEDASSSLRALGSTRAFTCHCR RSCYSTEYSYGTCTVMGINHRFCCL
• Sequence Similarities: Belongs to the alpha-defensin family.

Gene Information

• Gene Name: DEFA6 defensin, alpha 6, Paneth cell-specific [ Homo sapiens ]
• Official Symbol: DEFA6
• Synonyms: DEFA6; defensin, alpha 6, Paneth cell-specific; defensin-6; DEF6; HD 6
• Gene ID: 1671
• mRNA Refseq: NM_001926
• Protein Refseq: NP_001917
• MIM: 600471
• Uniprot ID: Q01524
• Chromosome Location: 8p23.1