"CDH1" Related Products


Recombinant Human Cadherin 1, Type 1, E-Cadherin (Epithelial)

Cat. No. : CDH1-1605H
Description : Cadherin 1, type 1, E-cadherin (epithelial), also known as CDH1 and CD32, is a tumor suppressor gene. The encoded protein is a calcium dependent cell-cell adhesion glycoprotein comprised of five extracellular cadherin repeats, a transmembrane region and a highly conserved cytoplasmic tail. E-cadherin-mediated cell-cell adhesion pathway may represent a novel chemotherapeutic target for bladder cancer, prostate cancer, and renal-cell carcinoma.
Source : NSO cells.
Molecular Weight : The predicted molecular weight of Recombinant Human E-Cadherin is 87.7 kDa. However, the actual molecular weight as observed by migration on SDS Page is 120 kDa.
State Of Matter : Lyophilized.
Purity : >90% by SDS Page and analyzed by silver stain.
Endotoxin : <1.0 EU/µg as determined by the LAL method.
Storage : This lyophilized protein is stable for six to twelve months when stored desiccated at -20℃ to -70℃. After aseptic reconstitution, this protein may be stored at 2℃ to 8℃ for one month or at -20℃ to -70℃ in a manual defrost freezer. Avoid Repeated Freeze Thaw Cycles. See Product Insert for exact lot specific storage instructions.
PDB rendering based on 1i7w. :

Gene Name : CDH1 cadherin 1, type 1, E-cadherin (epithelial) [ Homo sapiens ]
Synonyms : CDH1; cadherin 1, type 1, E-cadherin (epithelial); UVO; CDHE; ECAD; LCAM; Arc-1; CD324; cadherin 1, type 1; uvomorulin; cell-CAM 120/80; cadherin 1, E-cadherin (epithelial); calcium-dependent adhesion protein, epithelial; uvomorulin; Cadherin-1; E-cadherin; CAM 120/80; E-Cad/CTF1; E-Cad/CTF2; E-Cad/CTF3; Uvomorulin; CD324 antigen; Epithelial cadherin
Gene ID : 999
mRNA Refseq : NM_004360
Protein Refseq : NP_004351
MIM : 192090
UniProt ID : P12830
Chromosome Location : 16q22.1
Pathway : Adherens junction; Bladder cancer; Cell adhesion molecules (CAMs); Endometrial cancer; Melanoma; Pathogenic Escherichia coli infection - EHEC; Pathways in cancer; Thyroid cancer; Apoptosis; Cell-cell adhesion systems; Integrin cell surface interactions; Signaling in Immune system
Function : RPTP-like protein binding; beta-catenin binding; calcium ion binding; cell adhesion molecule binding; protein phosphatase binding; transcription activator activity

Online Inquiry

Note: There will be extra charge for optional service!

Please input "biomart" as verification code. Please review Creative BioMart's privacy policy for more information

Optional requirements on this protein    +Expand

Price Inquiry

Welcome! For price inquiries, please feel free to contact us through the form below. We will get back to you as soon as possible.