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Recombinant Human FLT3LG, His-tagged

Cat.No. : FLT3LG-28341TH
Product Overview : Recombinant fragment, corresponding to amino acids 27-181 of Human Flt3 ligand with His tag produced in the endosperm tissue of barley grain ; 156 amino acids, 19.8 kDa.
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  • Gene Information
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Description : Dendritic cells (DCs) provide the key link between innate and adaptive immunity by recognizing pathogens and priming pathogen-specific immune responses. FLT3LG controls the development of DCs and is particularly important for plasmacytoid DCs and CD8 (see MIM 186910)-positive classical DCs and their CD103 (ITGAE; MIM 604682)-positive tissue counterparts (summary by Sathaliyawala et al.
Conjugation : HIS
Biological activity : Bioactivity:The EC50 for FLT3LG-28341TH lies in the range of 0.12-0.18 ng/ml, corresponding to specific activity 6.62 x 106 U/mg. We recommend that the optimal concentration for each specific application be determined by an initial dose-response assay.
Form : Lyophilised:It is recommended to reconstitute the lyophilized protein in sterile phosphate-buffered saline to a concentration of no less than 100 μg/ml. For long term storage of the reconstituted solution it is recommended to add a carrier protein (0.1% H
Purity : >95% by SDS-PAGE
Storage buffer : Preservative: NoneConstituents: 10mM Acetic acid, pH 5.0
Storage : Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid repeated freeze / thaw cycles.
Gene Name : FLT3LG fms-related tyrosine kinase 3 ligand [ Homo sapiens ]
Official Symbol : FLT3LG
Synonyms : FLT3LG; fms-related tyrosine kinase 3 ligand;
Gene ID : 2323
mRNA Refseq : NM_001204502
Protein Refseq : NP_001191431
MIM : 600007
Uniprot ID : P49771
Chromosome Location : 19q13.3
Pathway : Cytokine-cytokine receptor interaction, organism-specific biosystem; Cytokine-cytokine receptor interaction, conserved biosystem; Hematopoietic cell lineage, organism-specific biosystem; Hematopoietic cell lineage, conserved biosystem; Pathways in cancer, organism-specific biosystem;
Function : cytokine activity; receptor binding;

For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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