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Recombinant Human GGA1, His-tagged

Cat.No. : GGA1-28744TH
Product Overview : Recombinant fragment, corresponding to amino acids 162-639 of Human GGA1 with an N-terminal His Tag, 478 amino acids, approximately 88kDa.
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  • Gene Information
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Description : This gene encodes a member of the Golgi-localized, gamma adaptin ear-containing, ARF-binding (GGA) protein family. Members of this family are ubiquitous coat proteins that regulate the trafficking of proteins between the trans-Golgi network and the lysosome. These proteins share an amino-terminal VHS domain which mediates sorting of the mannose 6-phosphate receptors at the trans-Golgi network. They also contain a carboxy-terminal region with homology to the ear domain of gamma-adaptins. Multiple alternatively spliced transcript variants encoding different isoforms have been found for this gene.
Conjugation : HIS
Source : E. coli
Form : Lyophilised:reconstitution with 101 μl aqua dest.
Storage buffer : Preservative: NoneConstituents: 0.5% Trehalose, 6M Urea, 100mM Sodium hydrogen phosphate, 10mM Sodium chloride, pH 4.5
Storage : Shipped at 4°C. Upon delivery aliquot and store at -80oC. Avoid freeze / thaw cycles.
Sequences of amino acids : PRPKNVIFEDEEKSKMLARLLKSSH PEDLRAANKLIKEMV QEDQKRMEKISKRVNAIEEVNNNVK LLTEMVMSHSQGG AAAGSSEDLMKELYQRCERMRPTLF RLASDTEDNDEALAE ILQANDNLTQVINLYKQLVRGEEVN GDATAGSIPGSTS ALLDLSGLDLPPAGTTYPAMPTRPG EQASPEQPSASVS LLDDELMSLGLSDPTPPSGPSLDGT GWNSFQSSDATEPPA PALAQAPSMESRPPAQTSLPASSGL DDLDLLGKTLLQQ SLPPESQQVRWEKQQPTPRLTLRDL QNKSSSCSSPSSSATSLLHTVSPEP PRPPQQPVPTELSLASITVPLESIK PSN ILPVTVYDQHGFRILFHFARDPLPG RSDVLVVVVSMLS TAPQPIRNIVFQSAVPKVMKVKLQP PSGTELPAFNPIVHP SAITQVLLLANPQKEKVRLRYKLTF TMGDQTYNEMGDV DQFPPPETWGSL
Gene Name : GGA1 golgi-associated, gamma adaptin ear containing, ARF binding protein 1 [ Homo sapiens ]
Official Symbol : GGA1
Synonyms : GGA1; golgi-associated, gamma adaptin ear containing, ARF binding protein 1; ADP-ribosylation factor-binding protein GGA1;
Gene ID : 26088
mRNA Refseq : NM_001001560
Protein Refseq : NP_001001560
MIM : 606004
Uniprot ID : Q9UJY5
Chromosome Location : 22q13.31
Pathway : Lysosome, organism-specific biosystem; Lysosome, conserved biosystem;
Function : molecular_function; protein binding;

For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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