||Full length Alanine Transaminase from human heart.
||This gene encodes cytosolic alanine aminotransaminase 1 (ALT1); also known as glutamate-pyruvate transaminase 1. This enzyme catalyzes the reversible transamination between alanine and 2-oxoglutarate to generate pyruvate and glutamate and, therefore, plays a key role in the intermediary metabolism of glucose and amino acids. Serum activity levels of this enzyme are routinely used as a biomarker of liver injury caused by drug toxicity, infection, alcohol, and steatosis. A related gene on chromosome 16 encodes a putative mitochondrial alanine aminotransaminase.
||Liver, kidney, heart, and skeletal muscles. Expressed at moderate levels in the adipose tissue.
||Specific activity:29 U/mg protein.
||Preservative: NoneConstituents: 100mM Sodium chloride, 10mM Tris HCl, 1mM EDTA, 1mM DTE, 10mM alpha-Ketoglutarate, 20μg/ml Pyridoxal-5-phosphate, pH 7.0
||Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.
||Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family. Alanine aminotransferase subfamily.