Recombinant Human MSI1

• Cat.No.: MSI1-30259TH
• Product Overview: Recombinant full length Human Musashi 1 / Msi1 with a proprietary tag; Predicted MWt 65.89 kDa including tag.

Specification

• Description: This gene encodes a protein containing two conserved tandem RNA recognition motifs. Similar proteins in other species function as RNA-binding proteins and play central roles in posttranscriptional gene regulation. Expression of this gene has been correlated with the grade of the malignancy and proliferative activity in gliomas and melanomas. A pseudogene for this gene is located on chromosome 11q13.
• Protein length: 362 amino acids
• Molecular Weight: 65.890kDa inclusive of tags
• Source: Wheat germ
• Tissue specificity: Detected in fetal kidney, brain, liver and lung, and in adult brain and pancreas. Detected in hepatoma cell lines.
• Form: Liquid
• Purity: Proprietary Purification
• Storage buffer: pH: 8.00Constituents:0.31% Glutathione, 0.79% Tris HCl
• Storage: Shipped on dry ice. Upon delivery aliquot and store at -80oC. Avoid freeze / thaw cycles.
• Sequences of amino acids: METDAPQPGLASPDSPHDPCKMFIG GLSWQTTQEGLREYFGQFGEVKECL VMRDPLTKRSRGFGFVTFMDQAGVD KVLAQSRHELDSKTIDPKVAFPRRA QPKMVTRTKKIFVGGLSVNTTVEDV KQYFEQFGKVDDAMLMFDKTTNRHR GFGFVTFESEDIVEKVCEIHFHEIN NKMVECKKAQPKEVMSPTGSARGRS RVMPYGMDAFMLGIGMLGYPGFQAT TYASRSYTGLAPGYTYQFPEFRVER TPLPSAPVLPELTAIPLTAYGPMAA AAAAAAVVRGTGSHPWTMAPPPGST PSRTGGFLGTTSPGPMAELYGAANQ DSGVSSYISAASPAPSTGFGHSLGG PLIATAFTNGYH
• Sequence Similarities: Belongs to the Musashi family.Contains 2 RRM (RNA recognition motif) domains.

Gene Information

• Gene Name: MSI1 musashi homolog 1 (Drosophila) [ Homo sapiens ]
• Official Symbol: MSI1
• Synonyms: MSI1; musashi homolog 1 (Drosophila); Musashi (Drosophila) homolog 1; RNA-binding protein Musashi homolog 1
• Gene ID: 4440
• mRNA Refseq: NM_002442
• Protein Refseq: NP_002433
• MIM: 603328
• Uniprot ID: O43347
• Chromosome Location: 12q24
• Pathway: mRNA surveillance pathway, organism-specific biosystem; mRNA surveillance pathway, conserved biosystem
• Function: RNA binding; nucleotide binding; poly(U) RNA binding; single-stranded RNA binding