Recombinant Human NCALD, His-tagged
Cat.No. : | NCALD-27853TH |
Product Overview : | Recombinant full length Human NCALD , with an N terminal His tag ; predicted mwt: 24.4 kDa. |
- Specification
- Gene Information
- Related Products
Description : | This gene encodes a member of the neuronal calcium sensor (NCS) family of calcium-binding proteins. The protein contains an N-terminal myristoylation signal and four EF-hand calcium binding loops. The protein is cytosolic at resting calcium levels; however, elevated intracellular calcium levels induce a conformational change that exposes the myristoyl group, resulting in protein association with membranes and partial co-localization with the perinuclear trans-golgi network. The protein is thought to be a regulator of G protein-coupled receptor signal transduction. Several alternatively spliced variants of this gene have been determined, all of which encode the same protein; additional variants may exist but their biological validity has not been determined. |
Protein length : | 193 amino acids |
Conjugation : | HIS |
Molecular Weight : | 24.400kDa inclusive of tags |
Source : | E. coli |
Tissue specificity : | Retina, cerebrum, cerebellum, brain stem, spinal cord, testis, ovary and small intestine. |
Form : | Liquid |
Purity : | >90% by SDS-PAGE |
Storage buffer : | Preservative: NoneConstituents: 40% Glycerol, 20mM Tris HCl, 100mM Sodium chloride, 1mM DTT, pH 8 |
Storage : | Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles. |
Sequences of amino acids : | MGSSHHHHHH SSGLVPRGSH MGKQNSKLRP EVMQDLLEST DFTEHEIQEW YKGFLRDCPS GHLSMEEFKK IYGNFFPYGD ASKFAEHVFRTFDANGDGTI DFREFIIALS VTSRGKLEQK LKWAFSMYDL DGNGYISKAE MLEIVQAIYK MVSSVMKMPE DESTPEKRTE KIFRQMDTNRDGKLSLEEFI RGAKSDPSIV RLLQCDPSSA GQF |
Sequence Similarities : | Belongs to the recoverin family.Contains 4 EF-hand domains. |
Gene Name : | NCALD neurocalcin delta [ Homo sapiens ] |
Official Symbol : | NCALD |
Synonyms : | NCALD; neurocalcin delta; neurocalcin-delta; |
Gene ID : | 83988 |
mRNA Refseq : | NM_001040624 |
Protein Refseq : | NP_001035714 |
MIM : | 606722 |
Uniprot ID : | P61601 |
Chromosome Location : | 8q22-q23 |
Pathway : | Activation of Ca-permeable Kainate Receptor, organism-specific biosystem; Activation of Kainate Receptors upon glutamate binding, organism-specific biosystem; Ionotropic activity of Kainate Receptors, organism-specific biosystem; Neuronal System, organism-specific biosystem; Neurotransmitter Receptor Binding And Downstream Transmission In ThePostsynaptic Cell, organism-specific biosystem; |
Function : | actin binding; calcium ion binding; clathrin binding; tubulin binding; |
Products Types
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NCALD-252H | Recombinant Human NCALD Protein, His-tagged | +Inquiry |
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◆ Lysates | ||
NCALD-3955HCL | Recombinant Human NCALD 293 Cell Lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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