||Recombinant Full Length Human PDE1B,, with N terminal enzyme tag. MW= 87 kDa. Expressed in a Baculovirus infected Sf9 cell expression system.
||The protein encoded by this gene belongs to the cyclic nucleotide phosphodiesterase (PDE) family, and PDE1 subfamily. Members of the PDE1 family are calmodulin-dependent PDEs that are stimulated by a calcium-calmodulin complex. This PDE has dual-specificity for the second messengers, cAMP and cGMP, with a preference for cGMP as a substrate. cAMP and cGMP function as key regulators of many important physiological processes. Alternatively spliced transcript variants encoding different isoforms have been described for this gene.
||Preservative: NoneConstituents: 50% Glycerol, 0.05% Tween 20, 3mM DTT, 25mM Tris HCl, 20mM Glutathione, 100mM Sodium chloride, pH 8.0
||Aliquot and store at -80°C. Avoid repeated freeze / thaw cycles.
||Belongs to the cyclic nucleotide phosphodiesterase family. PDE1 subfamily.