|Product Overview :
||Recombinant fragment corresponding to amino acids 107-450 of Human PDE7B with N terminal proprietary tag, expressed in a Baculovirus infected Sf9 cell expression system, 66 kDa
||The 3,5-cyclic nucleotides cAMP and cGMP function as second messengers in a wide variety of signal transduction pathways. 3,5-cyclic nucleotide phosphodiesterases (PDEs) catalyze the hydrolysis of cAMP and cGMP to the corresponding 5-monophosphates and provide a mechanism to downregulate cAMP and cGMP signaling. This gene encodes a cAMP-specific phosphodiesterase, a member of the cyclic nucleotide phosphodiesterase family.
|Biological activity :
||Specific Activity: 53 pmol/min/μg.
|Storage buffer :
||Preservative: NoneConstituents: 50% Glycerol, 0.05% Tween 20, 3mM DTT, 25mM Tris HCl, 100mM Sodium chloride, pH 8
||Aliquot and store at -80°C. Avoid repeated freeze / thaw cycles.