Recombinant Human PDE7B

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Recombinant Human PDE7B

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Cat.No. : PDE7B-30224TH
Product Overview : Recombinant fragment corresponding to amino acids 107-450 of Human PDE7B with N terminal proprietary tag, expressed in a Baculovirus infected Sf9 cell expression system, 66 kDa
Description : The 3,5-cyclic nucleotides cAMP and cGMP function as second messengers in a wide variety of signal transduction pathways. 3,5-cyclic nucleotide phosphodiesterases (PDEs) catalyze the hydrolysis of cAMP and cGMP to the corresponding 5-monophosphates and provide a mechanism to downregulate cAMP and cGMP signaling. This gene encodes a cAMP-specific phosphodiesterase, a member of the cyclic nucleotide phosphodiesterase family.
Biological activity : Specific Activity: 53 pmol/min/μg.
Form : Liquid
Storage buffer : Preservative: NoneConstituents: 50% Glycerol, 0.05% Tween 20, 3mM DTT, 25mM Tris HCl, 100mM Sodium chloride, pH 8
Storage : Aliquot and store at -80°C. Avoid repeated freeze / thaw cycles.
Gene Name : PDE7B phosphodiesterase 7B [ Homo sapiens ]
Official Symbol : PDE7B
Synonyms : PDE7B; phosphodiesterase 7B; cAMP-specific 3,5-cyclic phosphodiesterase 7B;
Gene ID : 27115
mRNA Refseq : NM_018945
Protein Refseq : NP_061818
MIM : 604645
Uniprot ID : Q9NP56
Chromosome Location : 6q23-q24
Pathway : G Protein Signaling Pathways, organism-specific biosystem; G alpha (s) signalling events, organism-specific biosystem; GPCR downstream signaling, organism-specific biosystem; Purine metabolism, organism-specific biosystem; Purine metabolism, conserved biosystem;
Function : 3,5-cyclic-AMP phosphodiesterase activity; hydrolase activity; metal ion binding; phosphoric diester hydrolase activity;
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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