"PDE7B" Related Products

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Recombinant Human PDE7B

Cat.No. : PDE7B-30224TH
Product Overview : Recombinant fragment corresponding to amino acids 107-450 of Human PDE7B with N terminal proprietary tag, expressed in a Baculovirus infected Sf9 cell expression system, 66 kDa
Description : The 3,5-cyclic nucleotides cAMP and cGMP function as second messengers in a wide variety of signal transduction pathways. 3,5-cyclic nucleotide phosphodiesterases (PDEs) catalyze the hydrolysis of cAMP and cGMP to the corresponding 5-monophosphates and provide a mechanism to downregulate cAMP and cGMP signaling. This gene encodes a cAMP-specific phosphodiesterase, a member of the cyclic nucleotide phosphodiesterase family.
Biological activity : Specific Activity: 53 pmol/min/μg.
Form : Liquid
Storage buffer : Preservative: NoneConstituents: 50% Glycerol, 0.05% Tween 20, 3mM DTT, 25mM Tris HCl, 100mM Sodium chloride, pH 8
Storage : Aliquot and store at -80°C. Avoid repeated freeze / thaw cycles.
Gene Name : PDE7B phosphodiesterase 7B [ Homo sapiens ]
Official Symbol : PDE7B
Synonyms : PDE7B; phosphodiesterase 7B; cAMP-specific 3,5-cyclic phosphodiesterase 7B;
Gene ID : 27115
mRNA Refseq : NM_018945
Protein Refseq : NP_061818
MIM : 604645
Uniprot ID : Q9NP56
Chromosome Location : 6q23-q24
Pathway : G Protein Signaling Pathways, organism-specific biosystem; G alpha (s) signalling events, organism-specific biosystem; GPCR downstream signaling, organism-specific biosystem; Purine metabolism, organism-specific biosystem; Purine metabolism, conserved biosystem;
Function : 3,5-cyclic-AMP phosphodiesterase activity; hydrolase activity; metal ion binding; phosphoric diester hydrolase activity;

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