Recombinant Human PDE7B

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Recombinant Human PDE7B

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Cat.No. : PDE7B-30823TH
Product Overview : Recombinant full length Human PDE7B with an N-terminal proprietary tag, expressed by Baculovirus in Sf9 insect cells; MWt 73 kDa.
Description : The 3,5-cyclic nucleotides cAMP and cGMP function as second messengers in a wide variety of signal transduction pathways. 3,5-cyclic nucleotide phosphodiesterases (PDEs) catalyze the hydrolysis of cAMP and cGMP to the corresponding 5-monophosphates and provide a mechanism to downregulate cAMP and cGMP signaling. This gene encodes a cAMP-specific phosphodiesterase, a member of the cyclic nucleotide phosphodiesterase family.
Protein length : 450 amino acids
Molecular Weight : 73.000kDa inclusive of tags
Source : Baculovirus
Biological activity : The specific activity of PDE7B is determined to be 28 nmol/min/mg.
Form : Liquid
Purity : by SDS-PAGE
Storage buffer : Preservative: NoneConstituents: 25% Glycerol, 50mM Tris HCl, 150mM Sodium chloride, 10mM Glutathione, 0.25mM DTT, 0.1mM EDTA, 0.1mM PMSF, pH 7.5
Storage : Shipped on dry ice. Upon delivery aliquot and store at -80oC. Avoid freeze / thaw cycles.
Gene Name : PDE7B phosphodiesterase 7B [ Homo sapiens ]
Official Symbol : PDE7B
Synonyms : PDE7B; phosphodiesterase 7B; cAMP-specific 3,5-cyclic phosphodiesterase 7B;
Gene ID : 27115
mRNA Refseq : NM_018945
Protein Refseq : NP_061818
MIM : 604645
Uniprot ID : Q9NP56
Chromosome Location : 6q23-q24
Pathway : G Protein Signaling Pathways, organism-specific biosystem; G alpha (s) signalling events, organism-specific biosystem; GPCR downstream signaling, organism-specific biosystem; Purine metabolism, organism-specific biosystem; Purine metabolism, conserved biosystem;
Function : 3,5-cyclic-AMP phosphodiesterase activity; hydrolase activity; metal ion binding; phosphoric diester hydrolase activity;
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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