Recombinant Human PFKM, His-tagged
Cat.No. : | PFKM-28952TH |
Product Overview : | Recombinant full length Human Fructose 6 Phosphate Kinase with an N-terminal His Tag; 800 amino acids with tag, MWt 87.3kDa. |
- Specification
- Gene Information
- Related Products
Description : | Three phosphofructokinase isozymes exist in humans: muscle, liver and platelet. These isozymes function as subunits of the mammalian tetramer phosphofructokinase, which catalyzes the phosphorylation of fructose-6-phosphate to fructose-1,6-bisphosphate. Tetramer composition varies depending on tissue type. This gene encodes the muscle-type isozyme. Mutations in this gene have been associated with glycogen storage disease type VII, also known as Tarui disease. Alternatively spliced transcript variants have been described. |
Conjugation : | HIS |
Source : | E. coli |
Form : | Liquid |
Storage buffer : | Preservative: NoneConstituents: 20% Glycerol, 0.2M Sodium chloride, 5mM DTT, 20mM Tris HCl, pH 8.0 |
Storage : | Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles. |
Sequences of amino acids : | MGSSHHHHHH SSGLVPRGSH MTHEEHHAAK TLGIGKAIAV LTSGGDAQGM NAAVRAVVRV GIFTGARVFF VHEGYQGLVD GGDHIKEATW ESVSMMLQLG GTVIGSARCK DFREREGRLR AAYNLVKRGI TNLCVIGGDG SLTGADTFRS EWSDLLSDLQ KAGKITDEEA TKSSYLNIVG LVGSIDNDFC GTDMTIGTDS ALHRIMEIVD AITTTAQSHQ RTFVLEVMGR HCGYLALVTS LSCGADWVFI PECPPDDDWE EHLCRRLSET RTRGSRLNII IVAEGAIDKN GKPITSEDIK NLVVKRLGYD TRVTVLGHVQ RGGTPSAFDR ILGSRMGVEA VMALLEGTPD TPACVVSLSG NQAVRLPLME CVQVTKDVTK AMDEKKFDEA LKLRGRSFMN NWEVYKLLAH VRPPVSKSGS HTVAVMNVGA PAAGMNAAVR STVRIGLIQG NRVLVVHDGF EGLAKGQIEE AGWSYVGGWT GQGGSKLGTK RTLPKKSFEQ ISANITKFNI QGLVIIGGFE AYTGGLELME GRKQFDELCI PFVVIPATVS NNVPGSDFSV GADTALNTIC TTCDRIKQSA AGTKRRVFII ETMGGYCGYL ATMAGLAAGA DAAYIFEEPF TIRDLQANVE HLVQKMKTTV KRGLVLRNEK CNENYTTDFI FNLYSEEGKG IFDSRKNVLG HMQQGGSPTP FDRNFATKMG AKAMNWMSGK IKESYRNGRI FANTPDSGCV LGMRKRALVF QPVAELKDQT DFEHRIPKEQ WWLKLRPILK ILAKYEIDLD TSDHAHLEHI TRKRSGEAAV |
Sequence Similarities : | Belongs to the phosphofructokinase family. Two domains subfamily. |
Gene Name : | PFKM phosphofructokinase, muscle [ Homo sapiens ] |
Official Symbol : | PFKM |
Synonyms : | PFKM; phosphofructokinase, muscle; PFKX, phosphofructokinase, polypeptide X; 6-phosphofructokinase, muscle type; PFK 1; |
Gene ID : | 5213 |
mRNA Refseq : | NM_000289 |
Protein Refseq : | NP_000280 |
MIM : | 610681 |
Uniprot ID : | P08237 |
Chromosome Location : | 12q13.11 |
Pathway : | Fructose and mannose metabolism, organism-specific biosystem; Fructose and mannose metabolism, conserved biosystem; Galactose metabolism, organism-specific biosystem; Galactose metabolism, conserved biosystem; Glucose metabolism, organism-specific biosystem; |
Function : | 6-phosphofructokinase activity; 6-phosphofructokinase activity; 6-phosphofructokinase activity; AMP binding; ATP binding; |
Products Types
◆ Recombinant Protein | ||
PFKM-4055R | Recombinant Rat PFKM Protein, His (Fc)-Avi-tagged | +Inquiry |
PFKM-2582H | Recombinant Human PFKM Protein, His-tagged | +Inquiry |
PFKM-6654M | Recombinant Mouse PFKM Protein, His (Fc)-Avi-tagged | +Inquiry |
Pfkm-4810M | Recombinant Mouse Pfkm Protein, Myc/DDK-tagged | +Inquiry |
PFKM-1653H | Recombinant Human PFKM Protein, His (Fc)-Avi-tagged | +Inquiry |
◆ Lysates | ||
PFKM-3271HCL | Recombinant Human PFKM 293 Cell Lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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