Recombinant Full Length Human PFKM Protein, C-Flag-tagged
Cat.No. : | PFKM-473HFL |
Product Overview : | Recombinant Full Length Human PFKM Protein, fused to Flag-tag at C-terminus, was expressed in Mammalian cells. |
- Specification
- Gene Information
- Related Products
Description : | Three phosphofructokinase isozymes exist in humans: muscle, liver and platelet. These isozymes function as subunits of the mammalian tetramer phosphofructokinase, which catalyzes the phosphorylation of fructose-6-phosphate to fructose-1,6-bisphosphate. Tetramer composition varies depending on tissue type. This gene encodes the muscle-type isozyme. Mutations in this gene have been associated with glycogen storage disease type VII, also known as Tarui disease. Alternatively spliced transcript variants have been described. |
Source : | Mammalian cells |
Species : | Human |
Tag : | Flag |
Form : | 25 mM Tris HCl, pH 7.3, 100 mM glycine, 10% glycerol. |
Molecular Mass : | 85 kDa |
AA Sequence : | MTHEEHHAAKTLGIGKAIAVLTSGG DAQGMNAAVRAVVRVGIFTGARVFF VHEGYQGLVDGGDHIKEATW ESVSMMLQLGGTVIGSARCKDFRER EGRLRAAYNLVKRGITNLCVIGGDG SLTGADTFRSEWSDLLSDLQ KAGKITDEEATKSSYLNIVGLVGSI DNDFCGTDMTIGTDSALHRIMEIVD AITTTAQSHQRTFVLEVMGR HCGYLALVTSLSCGADWVFIPECPP DDDWEEHLCRRLSETRTRGSRLNII IVAEGAIDKNGKPITSEDIK NLVVKRLGYDTRVTVLGHVQRGGTP SAFDRILGSRMGVEAVMALLEGTPD TPACVVSLSGNQAVRLPLME CVQVTKDVTKAMDEKKFDEALKLRG RSFMNNWEVYKLLAHVRPPVSKSGS HTVAVMNVGAPAAGMNAAVR STVRIGLIQGNRVLVVHDGFEGLAK GQIEEAGWSYVGGWTGQGGSKLGTK RTLPKKSFEQISANITKFNI QGLVIIGGFEAYTGGLELMEGRKQF DELCIPFVVIPATVSNNVPGSDFSV GADTALNTICTTCDRIKQSA AGTKRRVFIIETMGGYCGYLATMAG LAAGADAAYIFEEPFTIRDLQANVE HLVQKMKTTVKRGLVLRNEK CNENYTTDFIFNLYSEEGKGIFDSR KNVLGHMQQGGSPTPFDRNFATKMG AKAMNWMSGKIKESYRNGRI FANTPDSGCVLGMRKRALVFQPVAE LKDQTDFEHRIPKEQWWLKLRPILK ILAKYEIDLDTSDHAHLEHI TRKRSGEAAVTRTRPLEQKLISEED LAANDILDYKDDDDKV |
Purity : | > 80% as determined by SDS-PAGE and Coomassie blue staining. |
Stability : | Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles. |
Storage : | Store at -80 centigrade. |
Concentration : | >50 ug/mL as determined by microplate BCA method. |
Preparation : | Recombinant protein was captured through anti-DDK affinity column followed by conventional chromatography steps. |
Protein Families : | Druggable Genome |
Protein Pathways : | Fructose and mannose metabolism, Galactose metabolism, Glycolysis / Gluconeogenesis, Metabolic pathways, Pentose phosphate pathway |
Gene Name : | PFKM phosphofructokinase, muscle [ Homo sapiens (human) ] |
Official Symbol : | PFKM |
Synonyms : | GSD7; PFK1; PFKA; PFKX; PFK-1; PFK-A; ATP-PFK; PPP1R122 |
Gene ID : | 5213 |
mRNA Refseq : | NM_000289.6 |
Protein Refseq : | NP_000280.1 |
MIM : | 610681 |
UniProt ID : | P08237 |
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◆ Lysates | ||
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For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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