||Recombinant full length protein: Human PSMC6 fused with a T7 tag at N-terminus.
||The 26S proteasome is a multicatalytic proteinase complex with a highly ordered structure composed of 2 complexes, a 20S core and a 19S regulator. The 20S core is composed of 4 rings of 28 non-identical subunits; 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. The 19S regulator is composed of a base, which contains 6 ATPase subunits and 2 non-ATPase subunits, and a lid, which contains up to 10 non-ATPase subunits. Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin-dependent process in a non-lysosomal pathway.An essential function of a modified proteasome, the immunoproteasome, is the processing of class I MHC peptides. This gene encodes one of the ATPase subunits, a member of the triple-A family of ATPases which have a chaperone-like activity. Pseudogenes have been identified on chromosomes 8 and 12.
||>95% by SDS-PAGE
||Preservative: 0.002% Sodium AzideConstituents: 0.1% Triton-X-100, 10mM Tris, pH 8.0
||Aliquot and store at -80°C. Avoid repeated freeze / thaw cycles.
||Belongs to the AAA ATPase family.