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Recombinant Mouse Interleukin 5

Cat. No.: Il5-224M
Description: Interleukin 5 or IL-5 is an interleukin produced by T helper-2 cells and mast cells. Its functions are to stimulate B cell growth and increase immunoglobulin secretion. It is the main factor that promotes the terminal differentiation of eosinophil progenitors and enhances the effector capacity of mature eosinophils. IL-5 is a TH2 cytokine which is part of the hematopoietic family. Unlike other members of this cytokine family in its active form, this glycoprotein is a homodimer. IL-5 expression is regulated by several transcription factors including GATA-3.
Source: Sf 21 Insect Cells.
Molecular Weight: The predicted molecular weight of Recombinant Mouse IL-5 is Mr 32-34 kDa.
State Of Matter: Solution.
Purity: >97% by SDS Page and analyzed by silver stain.
Endotoxin: <1.0 EU/µg as determined by the LAL method.
Storage And Stability: -20°C to -70°C.
Gene Name: Il5 interleukin 5 [ Mus musculus ]
Synonyms: Il5; interleukin 5; Il-5; OTTMUSP00000005818
Gene ID: 16191
mRNA Refseq: NM_010558
Protein Refseq: NP_034688
UniProt ID: P04401
Chromosome Location: 11 A5/B1; 11 29.2 cM
Pathway: Allograft rejection; Autoimmune thyroid disease; Cytokine-cytokine receptor interaction; Fc epsilon RI signaling pathway; Hematopoietic cell lineage; Jak-STAT signaling pathway; T cell receptor signaling pathway
Function: cytokine activity; growth factor activity; interleukin-5 receptor binding

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