|Cat. No. :
||Jagged 1 (JAG1) is a cell surface protein that functions in an embryologically important signaling pathway, known as the Notch signaling pathway, which is a highly conserved cell signaling system. JAG1 plays an essential role in tissue formation during embryonic development of primitive organisms. JAG1 is a strong candidate gene for Alagille syndrome (AGS) which is an autosomal dominant disorder with developmental abnormalities affecting the liver, heart, eyes, vertebrae, and craniofacial region.
|Molecular Weight :
||The predicted molecular weight of Recombinant Rat Jagged 1 is Mr 141.7 kDa. However, the actual molecular weight as observed by migration on SDS Page is Mr 180 kDa.
|State Of Matter :
||>90% by SDS Page and analyzed by silver stain.
||<1.0 EU/µg as determined by the LAL method.
|Storage And Stability :
||This lyophilized protein is stable for six to twelve months when stored desiccated at -20°Cto -70°C. After aseptic reconstitution, this protein may be stored at 2°Cto 8°Cfor one month or at -20°Cto -70°Cin a manual defrost freezer. Avoid Repeated Freeze Thaw Cycles. See Product Insert for exact lot specific storage instructions.