Recombinant Human SLC26A4
Cat.No. : | SLC26A4-31416TH |
Product Overview : | Recombinant fragment of Human SLC26A4 with N terminal proprietary tag; Predicted MW 34.54 kDa. |
- Specification
- Gene Information
- Related Products
Description : | Mutations in this gene are associated with Pendred syndrome, the most common form of syndromic deafness, an autosomal-recessive disease. It is highly homologous to the SLC26A3 gene; they have similar genomic structures and this gene is located 3 of the SLC26A3 gene. The encoded protein has homology to sulfate transporters. |
Protein length : | 81 amino acids |
Molecular Weight : | 34.540kDa inclusive of tags |
Source : | Wheat germ |
Tissue specificity : | High expression in adult thyroid, lower expression in adult and fetal kidney and fetal brain. Not expressed in other tissues. |
Form : | Liquid |
Purity : | Proprietary Purification |
Storage buffer : | pH: 8.00Constituents:0.3% Glutathione, 0.79% Tris HCl |
Storage : | Shipped on dry ice. Upon delivery aliquot and store at -80oC. Avoid freeze / thaw cycles. |
Sequences of amino acids : | RSLRVIVKEFQRIDVNVYFASLQDY VIEKLEQCGFFDDNIRKDTFFLTVH DAILYLQNQVKSQEGQGSILETITL IQDCKD |
Sequence Similarities : | Belongs to the SLC26A/SulP transporter (TC 2.A.53) family.Contains 1 STAS domain. |
Gene Name : | SLC26A4 solute carrier family 26, member 4 [ Homo sapiens ] |
Official Symbol : | SLC26A4 |
Synonyms : | SLC26A4; solute carrier family 26, member 4; DFNB4; pendrin; PDS; |
Gene ID : | 5172 |
mRNA Refseq : | NM_000441 |
Protein Refseq : | NP_000432 |
MIM : | 605646 |
Uniprot ID : | O43511 |
Chromosome Location : | 7q31 |
Pathway : | Multifunctional anion exchangers, organism-specific biosystem; SLC-mediated transmembrane transport, organism-specific biosystem; Transmembrane transport of small molecules, organism-specific biosystem; Transport of inorganic cations/anions and amino acids/oligopeptides, organism-specific biosystem; |
Function : | chloride transmembrane transporter activity; iodide transmembrane transporter activity; secondary active sulfate transmembrane transporter activity; sulfate transmembrane transporter activity; transporter activity; |
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Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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