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Recombinant Human SLC26A4

Cat.No. : SLC26A4-31416TH
Product Overview : Recombinant fragment of Human SLC26A4 with N terminal proprietary tag; Predicted MW 34.54 kDa.
  • Specification
  • Gene Information
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Description : Mutations in this gene are associated with Pendred syndrome, the most common form of syndromic deafness, an autosomal-recessive disease. It is highly homologous to the SLC26A3 gene; they have similar genomic structures and this gene is located 3 of the SLC26A3 gene. The encoded protein has homology to sulfate transporters.
Protein length : 81 amino acids
Molecular Weight : 34.540kDa inclusive of tags
Source : Wheat germ
Tissue specificity : High expression in adult thyroid, lower expression in adult and fetal kidney and fetal brain. Not expressed in other tissues.
Form : Liquid
Purity : Proprietary Purification
Storage buffer : pH: 8.00Constituents:0.3% Glutathione, 0.79% Tris HCl
Storage : Shipped on dry ice. Upon delivery aliquot and store at -80oC. Avoid freeze / thaw cycles.
Sequences of amino acids : RSLRVIVKEFQRIDVNVYFASLQDY VIEKLEQCGFFDDNIRKDTFFLTVH DAILYLQNQVKSQEGQGSILETITL IQDCKD
Sequence Similarities : Belongs to the SLC26A/SulP transporter (TC 2.A.53) family.Contains 1 STAS domain.
Gene Name : SLC26A4 solute carrier family 26, member 4 [ Homo sapiens ]
Official Symbol : SLC26A4
Synonyms : SLC26A4; solute carrier family 26, member 4; DFNB4; pendrin; PDS;
Gene ID : 5172
mRNA Refseq : NM_000441
Protein Refseq : NP_000432
MIM : 605646
Uniprot ID : O43511
Chromosome Location : 7q31
Pathway : Multifunctional anion exchangers, organism-specific biosystem; SLC-mediated transmembrane transport, organism-specific biosystem; Transmembrane transport of small molecules, organism-specific biosystem; Transport of inorganic cations/anions and amino acids/oligopeptides, organism-specific biosystem;
Function : chloride transmembrane transporter activity; iodide transmembrane transporter activity; secondary active sulfate transmembrane transporter activity; sulfate transmembrane transporter activity; transporter activity;

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For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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