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Recombinant Mouse Oncostatin M

Cat. No.: Osm-1771M
Description: Oncostatin M (OSM) is a cytokine produced by activated T lymphocytes and macrophages. The biological activities of OSM are mediated through two types of receptor complexes, the LIF/OSM shared receptor (type I) and OSM-specific receptor (OSM-R, type II).
Source: NSO Cells.
Molecular Weight: The predicted molecular weight of Recombinant Mouse OSM Rβ is Mr 109 kDa. However, the actual molecular weight as observed by migration on SDS Page is Mr >150 kDa.
State Of Matter: Lyophilized.
Purity: >90% by SDS Page and analyzed by silver stain.
Endotoxin: <1.0 EU/µg as determined by the LAL method.
Storage And Stability: This lyophilized protein is stable for six to twelve months when stored desiccated at -20°C to -70°C. After aseptic reconstitution, this protein may be stored at 2°C to 8°C for one month or at -20°C to -70°C in a manual defrost freezer. Avoid Repeated Freeze Thaw Cycles.
Gene Name: Osm oncostatin M [ Mus musculus ]
Synonyms: Osm; oncostatin M; OTTMUSP00000005249
Gene ID: 18413
mRNA Refseq: NM_001013365
Protein Refseq: NP_001013383
UniProt ID: P53347
Chromosome Location: 11 A1; 11 1.0 cM
Pathway: Cytokine-cytokine receptor interaction; Jak-STAT signaling pathway
Function: cytokine activity

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Optional requirements on this protein    +Expand
C-fusion    N-fusion   Non-tagged
His    GST   Fc   Others
<1.0 eu/μg    <0.1 eu/μg   <0.01 eu/μg   Not required
Monomer Isolation    Dimer Isolation    Not required
>80% by SDS-PAGE    >90% by SDS-PAGE   >95% by SDS-PAGE   Others

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