"PAK7" Related Products

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Recombinant Human P21 Protein (Cdc42/Rac)-Activated Kinase 7

Cat. No.: PAK7-522H
Product Overview: Recombinant Human PAK7 (amino acids 425-719) was expressed inE.coli.MW=33.9 kDa.
Description: PAK7 (also known as PAK5) is a novel human PAK family kinase that contains a CDC42/Rac1 interactive binding (CRIB) motif at the N-terminus and a Ste20-like kinase domain at the C-terminus. The p21-activated kinase (PAK) family of protein kinases has recently attracted considerable attention as an effector of Rho family of small G proteins and as an upstream regulator of MAPK signalling pathways during cellular events such as re-arrangement of the cytoskeleton and apoptosis. PAK7 like the other Paks has been implicated in the regulation of cell morphology, motility and transformation.
Source: E.Coli.
Formulated In: 25 mM Tris-HCl, pH 8.0, 150 mM NaCl, 10% glycerol, and 5 mM DTT.
Application: Useful for the study of enzyme kinetics, screening inhibitors, and selectivity profiling.
Stability: >6 months at -80°C.
Gene Name: PAK7 p21 protein (Cdc42/Rac)-activated kinase 7 [ Homo sapiens ]
Synonyms: PAK7; p21 protein (Cdc42/Rac)-activated kinase 7; PAK5; KIAA1264; MGC26232; OTTHUMP00000030260; p21(CDKN1A)-activated kinase 7; p21-activated kinase 7; p21CDKN1A-activated kinase 7; protein kinase PAK5; serine/threonine-protein kinase PAK7; EC 2.7.11.1
Gene ID: 57144
mRNA Refseq: NM_020341
Protein Refseq: NP_065074
MIM: 608038
UniProt ID: Q9P286
Chromosome Location: 20p12
Pathway: Axon guidance; ErbB signaling pathway; Focal adhesion; Regulation of actin cytoskeleton; Renal cell carcinoma; T cell receptor signaling pathway
Function: ATP binding; nucleotide binding; protein binding; protein serine/threonine kinase activity; transferase activity

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Optional requirements on this protein    +Expand
C-fusion    N-fusion   Non-tagged
His    GST   Fc   Others
<1.0 eu/μg    <0.1 eu/μg   <0.01 eu/μg   Not required
Monomer Isolation    Dimer Isolation    Not required
>80% by SDS-PAGE    >90% by SDS-PAGE   >95% by SDS-PAGE   Others

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