Recombinant Human Phosphodiesterase 7B, GST-tagged

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Recombinant Human Phosphodiesterase 7B, GST-tagged

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Cat. No. : PDE7B-446H
Product Overview : Recombinant Human phosphodiesterase 7B, full length with N-terminal GST tag expressed in aBaculovirusinfected Sf9 cell expression system. MW= 66 kDa.
Description : The 3",5"-cyclic nucleotides cAMP and cGMP function as second messengers in a wide variety of signal transduction pathways. 3",5"-cyclic nucleotide phosphodiesterases (PDEs) catalyze the hydrolysis of cAMP and cGMP to the corresponding 5"-monophosphates and provide a mechanism to downregulate cAMP and cGMP signaling. This gene encodes a cAMP-specific phosphodiesterase, a member of the cyclic nucleotide phosphodiesterase family.
Source : Baculovirus infected Sf9 cell.
Purity : >80%.
Application : Useful for the study of enzyme kinetics, screening inhibitors, and selectivity profiling.
Formulated In : 25 mM Tris-HCl, pH 8.0, 100 mM NaCl, 0.05% Tween-20, 50% glycerol, and 3 mM DTT.
Stability : >6 months at –80°C.
Gene Name : PDE7B phosphodiesterase 7B [ Homo sapiens ]
Synonyms : PDE7B; phosphodiesterase 7B; MGC88256; bA472E5.1; cAMP-specific 3",5"-cyclic phosphodiesterase 7B; EC 3.1.4.17; rolipram-insensitive phosphodiesterase type 7; high-affinity cAMP-specific 3",5"-cyclic phosphodiesterase
Gene ID : 27115
mRNA Refseq : NM_018945
Protein Refseq : NP_061818
MIM : 604645
UniProt ID : Q9NP56
Chromosome Location : 6q23-q24
Pathway : Progesterone-mediated oocyte maturation; Purine metabolism; Signaling by GPCR
Function : 3",5"-cyclic-AMP phosphodiesterase activity; hydrolase activity
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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