||Recombinant Human phosphodiesterase 7B, full length with N-terminal GST tag expressed in aBaculovirusinfected Sf9 cell expression system. MW= 66 kDa.
||The 3",5"-cyclic nucleotides cAMP and cGMP function as second messengers in a wide variety of signal transduction pathways. 3",5"-cyclic nucleotide phosphodiesterases (PDEs) catalyze the hydrolysis of cAMP and cGMP to the corresponding 5"-monophosphates and provide a mechanism to downregulate cAMP and cGMP signaling. This gene encodes a cAMP-specific phosphodiesterase, a member of the cyclic nucleotide phosphodiesterase family.
||Baculovirus infected Sf9 cell.
||Useful for the study of enzyme kinetics, screening inhibitors, and selectivity profiling.
||25 mM Tris-HCl, pH 8.0, 100 mM NaCl, 0.05% Tween-20, 50% glycerol, and 3 mM DTT.
||>6 months at –80°C.