||Recombinant full length human VEGFC expressed in modified human 293 cells; secreted disulfide linked antiparallel homodimer; 45-55kDa.
||The protein encoded by this gene is a member of the platelet-derived growth factor/vascular endothelial growth factor (PDGF/VEGF) family, is active in angiogenesis and endothelial cell growth, and can also affect the permeability of blood vessels.This secreted protein undergoes a complex proteolytic maturation, generating multiple processed forms which bind and activate VEGFR-3 receptors. Only the fully processed form can bind and activate VEGFR-2 receptors. This protein is structurally and functionally similar to vascular endothelial growth factor D.
||Lyophilised:It is recommended that 0.5 ml of sterile phosphate-buffered saline be added to the vial.Following reconstitution short-term storage at 4°C is recommended, and longer-term storage of aliquots at -18 to -20°C. Repeated freeze thawing is not reco
||>95% by SDS-PAGE
||Preservative: NoneConstituents: 10% Trehalose, 1% Human serum albumin
||Store at +4°C.
|Sequences of amino acids:
||TheoreticalSequence:FESGLDLSDAEPDAGEAT AYASKDLEEQLRSVSSVDELMTVLYPEYWKMYKCQLRK GGWQHNREQANLNSRTEETIKFAAAHYNTEILKSIDNEWRKTQCMPREVCIDVGKEFGVATNTFFKPPCVSVYRCGGC CNSEGLQCMNTSTSYLSKTLFEITVPLSQGPKPVTISF ANHTSCRCMSKLDVYRQVHSIIRRDisulfide bonded to:SLPATLPQCQAANKTCPTNYMWNNHICRCLAQEDF MFSSDAGDDSTDGFHDICGPNKELDEETCQCVCRAGLR PASCGPHKELDRNSCQCVCKNKLFPSQCGANREFDENT CQCVCKRTCPRNQPLNPGKCACECTESPQKCLLKGKKF HHQTCSCYRRPCTNRQKACEPGFSYSEEVCRCVPSYWKRPQMSNote: N-terminal sequences confirmed by Edman sequencing.