Recombinant Mouse Tnfrsf1a

• Cat.No.: Tnfrsf1a-1780M

Specification

• Cat. No.: Tnfrsf1a-1780M
• Description: Tumor necrosis factor receptor superfamily, member 1A, (TNFRI) also known as TNFRSF1A or CD120A is the principal receptor through which many of the pro-inflammatory activities of TNF-alpha are mediated. TNFRI contains a death domain through which it interacts with other death-domain proteins to promote cellular responses.
• Source: Mammalian cells
• Molecular Weight: The predicted molecular weight of Recombinant Mouse TNF RI is Mr 48.6 kDa. However, the actual molecular weight as observed by migration on SDS Page is Mr 70 kDa.
• State Of Matter: Lyophilized
• Purity: >90% by SDS Page and analyzed by silver stain.
• Endotoxin: <1.0 EU/µg as determined by the LAL method
• Storage And Stability: This lyophilized protein is stable for six to twelve months when stored desiccated at -20°C to -70°C. After aseptic reconstitution, this protein may be stored at 2°C to 8°C for one month or at -20°C to -70°C in a manual defrost freezer. Avoid Repeated Freeze Thaw Cycles. See Product Insert for exact lot specific storage instructions.

Gene Information

• Gene Name: Tnfrsf1a tumor necrosis factor receptor superfamily, member 1a [ Mus musculus ]
• Synonyms: Tnfrsf1a; tumor necrosis factor receptor superfamily, member 1a; FPF; p55; TNF-R; TNFAR; TNFRI; Tnfr1; p55-R; CD120a; TNF-R1; TNFR60; Tnfr-2; TNF-R-I; TNF-R55; TNFRp55; TNF-alphaR1; TNFalpha-R1; TNF receptor alpha chain; OTTMUSP00000028139
• Gene ID: 21937
• mRNA Refseq: NM_011609
• Protein Refseq: NP_035739
• UniProt ID: P25118
• Chromosome Location: 6 F3; 6 60.55 cM
• Pathway: Adipocytokine signaling pathway; Alzheimer"s disease; Amyotrophic lateral sclerosis (ALS); Apoptosis; Cytokine-cytokine receptor interaction; MAPK signaling pathway
• Function: protein binding; receptor activity; tumor necrosis factor receptor activity