|Cat. No. :
|Product Overview :
||Recombinant Mouse CXCL4 produced inE.Coliis a single, non-glycosylated polypeptide chain containing 73 amino acids and having a molecular mass of 8.2 kDa.
||Platelet factor-4 is a 70-amino acid protein that is released from the alpha-granules of activated platelets and binds with high affinity to heparin. Its major physiologic role appears to be neutralization of heparin-like molecules on the endothelial surface of blood vessels, thereby inhibiting local antithrombin III activity and promoting coagulation. As a strong chemoattractant for neutrophils and fibroblasts, PF4 probably has a role in inflammation and wound repair. Oncostatin-A is a member of the CXC chemocinfamily. Human PF4 is used for the proof of heparin-induced thrombocytopenia. Furthermore it is used as an inhibitor in the angiogenesis during tumor therapy.
|Amino Acid Sequence :
||MGPEESD GDLSCVCVKT ISSGIHLKHI TSLEVIKAGR HCAVPQLIAT LKNGRKICLD RQAPLYKKVI KKILES.
|Physical Appearance :
||Sterile Filtered white lyophilized powder.
||The Mouse CXCL4 protein was lyophilized from 1x PBS pH-7.4.
||Mouse CXCL4 although stable at 25°C 1 week, should be stored desiccated below -18°C. Please prevent freeze-thaw cycles.