"Pf4" Related Products

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Recombinant Mouse Platelet Factor 4

Cat. No. : Pf4-152M
Product Overview : Recombinant Mouse CXCL4 produced inE.Coliis a single, non-glycosylated polypeptide chain containing 73 amino acids and having a molecular mass of 8.2 kDa.
Description : Platelet factor-4 is a 70-amino acid protein that is released from the alpha-granules of activated platelets and binds with high affinity to heparin. Its major physiologic role appears to be neutralization of heparin-like molecules on the endothelial surface of blood vessels, thereby inhibiting local antithrombin III activity and promoting coagulation. As a strong chemoattractant for neutrophils and fibroblasts, PF4 probably has a role in inflammation and wound repair. Oncostatin-A is a member of the CXC chemocinfamily. Human PF4 is used for the proof of heparin-induced thrombocytopenia. Furthermore it is used as an inhibitor in the angiogenesis during tumor therapy.
Source : Escherichia Coli.
Amino Acid Sequence : MGPEESD GDLSCVCVKT ISSGIHLKHI TSLEVIKAGR HCAVPQLIAT LKNGRKICLD RQAPLYKKVI KKILES.
Physical Appearance : Sterile Filtered white lyophilized powder.
Formulation : The Mouse CXCL4 protein was lyophilized from 1x PBS pH-7.4.
Stability : Mouse CXCL4 although stable at 25°C 1 week, should be stored desiccated below -18°C. Please prevent freeze-thaw cycles.
Gene Name : Pf4 platelet factor 4 [ Mus musculus ]
Synonyms : Pf4; platelet factor 4; Cxcl4; Scyb4; PF-4; C-X-C motif chemokine 4; chemokine (C-X-C motif) ligand 4
Gene ID : 56744
mRNA Refseq : NM_019932
Protein Refseq : NP_064316
UniProt ID : Q9Z126
Chromosome Location : 5 E1
Pathway : Chemokine signaling pathway; Cytokine-cytokine receptor interaction
Function : chemokine activity; cytokine activity; heparin binding

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