Creative BioMart to Present at
                        BIO-Europe Spring Creative BioMart to Present at AACR Annual Meeting|Apr. 5-10, 2024|Booth #2953

Recombinant Human DEK, GST-tagged

Cat.No. : DEK-2046H
Product Overview : Recombinant human DEK protein with a GST tag produced in E. coli.
  • Specification
  • Gene Information
  • Related Products
Description : This gene encodes a protein with one SAP domain. This protein binds to cruciform and superhelical DNA and induces positive supercoils into closed circular DNA, and is also involved in splice site selection during mRNA processing. Chromosomal aberrations involving this region, increased expression of this gene, and the presence of antibodies against this protein are all associated with various diseases. Two transcript variants encoding different isoforms have been found for this gene.
Source : E. coli
Species : Human
Tag : GST
Molecular Mass : ~ 70-kDa
Purity : > 90% by SDS-PAGE
Storage : Maintain preparations in aliquots at -70° C. Avoid repeated thawing.
Storage Buffer : 1 μg in 50 μl 50 mM Tris-HCl pH 7.0 buffer containing 14 mM β-mercaptoethanol, 1 mM benzamidine, 0.1 mM phenylmethanesulfonyl fluoride, 1 mM EDTA and 10% glycerol.
Gene Name : DEK DEK proto-oncogene [ Homo sapiens (human) ]
Official Symbol : DEK
Synonyms : DEK; D6S231E; DEK proto-oncogene; protein DEK; DEK oncogene (DNA binding)
Gene ID : 7913
mRNA Refseq : NM_001134709
Protein Refseq : NP_001128181
MIM : 125264
UniProt ID : P35659
Chromosome Location : 6p22.3
Function : DNA binding; histone binding; poly(A) RNA binding

For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

Inquiry

  • Q&As
  • Reviews

Q&As (5)

Ask a question
What are the current diagnostic methods for assessing DEK protein levels in clinical samples? 04/01/2022

Enzyme-linked immunosorbent assay (ELISA) and immunohistochemistry are commonly used to measure DEK protein levels in clinical samples from cancer and autoimmune disease patients.

How does DEK protein contribute to the pathogenesis of autoimmune diseases? 07/23/2021

DEK protein has been shown to play a role in aberrant immune responses, leading to the development of autoimmune diseases such as lupus and rheumatoid arthritis.

How does DEK protein interact with other cellular proteins in cancer and autoimmune diseases? 01/26/2021

DEK protein has been shown to interact with various cellular proteins, modulating signaling pathways and gene expression patterns associated with cancer and autoimmune diseases.

Are there any specific genetic mutations associated with DEK protein dysregulation in cancer? 07/12/2019

Mutations in the DEK gene and its regulatory regions have been identified in certain cancers, contributing to its aberrant expression and oncogenic potential.

Can DEK protein levels in patient samples predict treatment response in cancer therapy? 10/15/2017

Studies have suggested that DEK protein levels in patient samples may serve as predictive biomarkers for treatment response and resistance in cancer therapy.

Customer Reviews (3)

Write a review
Reviews
08/27/2021

    This collaboration may extend beyond the purchase of the DEK protein, potentially leading to additional support, joint research projects, or access to expertise in the field.

    12/20/2019

      This may include providing detailed protocols, troubleshooting advice, and suggestions for experimental design.

      08/13/2016

        The manufacturer can provide researchers with high-quality DEK protein, ensuring it is properly purified, characterized, and quality-controlled.

        Ask a Question for All DEK Products

        Required fields are marked with *

        My Review for All DEK Products

        Required fields are marked with *

        0

        Inquiry Basket

        cartIcon
        logo

        FOLLOW US

        Terms and Conditions        Privacy Policy

        Copyright © 2024 Creative BioMart. All Rights Reserved.

        Contact Us

        • /

        Stay Updated on the Latest Bioscience Trends