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Recombinant Human SET Nuclear Oncogene

Cat.No. : SET-2047H
Product Overview : Recombinant human I2PP2A(b) was produced inE. coli,41kDa.
  • Specification
  • Gene Information
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Cat. No. : SET-2047H
Description : I2PP2A(b), also termed TAF-1a, inhibits protein phosphatase 2A potently with ki ~ 0.1 - 0.5 nM with myelin basic protein, histone H1 and other substrates but not with casein. It stimulates PP1 and regulates histone binding to DNA, transcriptional activity and chromatin condensation.
Source : E. coli.
Purity : > 90% by SDS-PAGE.
Supplied : 250 ng in 50 ml 50 mM Tris-HCl pH 7.0 buffer containing 14 mM b-mercaptoethanol, 1 mM benzamidine, 0.1 mM phenylmethanesulfonyl fluoride, 1 mM EDTA and 0.1% Brij-35 and 10% glycerol.
Storage : Maintain preparations in aliquots at -70 °C. Avoid repeated thawing.
Gene Name : SET SET nuclear oncogene [ Homo sapiens ]
Synonyms : SET nuclear oncogene; 2PP2A; IGAAD; TAF-I; I2PP2A; IPP2A2; PHAPII; TAF-IBETA; SET; protein SET; I-2PP2A; HLA-DR-associated protein II; template-activating factor I; phosphatase 2A inhibitor I2PP2A; inhibitor-2 of protein phosphatase-2A; protein phosphatase type 2A inhibitor; inhibitor of granzyme A-activated DNase; SET translocation (myeloid leukemia-associated);Template-Activating Factor-I, chromatin remodelling factor; Inhibitor of granzyme A-activated DNase; Template-activating factor I; Phosphatase 2A inhibitor I2PP2A
Gene ID : 6418
mRNA Refseq : NM_001122821
Protein Refseq : NP_001116293
MIM : 600960
UniProt ID : Q01105
Chromosome Location : 9q34
Function : phosphoprotein phosphatase inhibitor activity; protein phosphatase type 2A regulator activity; histone binding; protein binding

For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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