|Product Overview:||Recombinant human B7H1 extracellular domain (C-terminus fused with murine IgG1 Fc)produced inmammalian cells contains 493 amino acids with predicted MW 56.06 KD x 2 (dimer), and 13 cysteines (Fc has 6). It also has 4 N-link glycosylation sites with MW increase up to 20 KD x 2 (dimer).|
|Description:||B7-H1 is a third member of the B7 family. It co-stimulates T-cell proliferation and interleukin-10 secretion. CD274 (Cluster of Differentiation 274) also known as PD-L1 (Programed Death Ligand-1) or B7-H1 is a protein which in humans is encoded by the CD274 gene.|
|Recommended Storage Temperature:||-70 °C.|
|Gene Name:||CD274 CD274 molecule [ Homo sapiens ]|
|Synonyms:||CD274; CD274 molecule; B7-H; B7H1; PDL1; PD-L1; PDCD1L1; PDCD1LG1; MGC142294; MGC142296; programmed cell death 1 ligand 1; CD274 antigen; Programmed cell death 1 ligand 1; Programmed death ligand 1; PDCD1 ligand 1; B7 homolog 1; OTTHUMP00000021029|
|Pathway:||Cell adhesion molecules (CAMs); Signaling in Immune system|
|Function:||protein binding; receptor activity|
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