Recombinant Rat Calpain 2, His tagged
| Cat.No. : | Capn2-2632R |
| Product Overview : | Recombinant Rat Calpain 2 with His tag was expressed in E. coli. |
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| Description : | Enables calcium ion binding activity; cytoskeletal protein binding activity; and enzyme binding activity. Contributes to calcium-dependent cysteine-type endopeptidase activity. Involved in several processes, including cellular response to interferon-beta; positive regulation of cell death; and positive regulation of myoblast fusion. Located in several cellular components, including external side of plasma membrane; focal adhesion; and neuronal cell body. Colocalizes with mitochondrial intermembrane space. Biomarker of hypertrophic cardiomyopathy and sciatic neuropathy. Orthologous to human CAPN2 (calpain 2). |
| Source : | E. coli |
| Species : | Rat |
| Tag : | N-His |
| Molecular Mass : | The protein has a calculated MW of 80 kDa. |
| AA Sequence : | MGSSHHHHHHSSGLVPRGSHMSHER AIKYLNQDYETLRNECLEAGALFQD PSFPALPSSLGFKELGPYSSKTRGI EWKRPTEICADPQFIIGGATRTDIC QGALGDCWLLAAIASLTLNEEILAR VVPLDQSFQENYAGIFHFQFWQYGE WVEVVVDDRLPTKDGELLFVHSAEG SEFWSALLEKAYAKINGCYEALSGG ATTEGFEDFTGGIAEWYELRKPPPN LFKIIQKALEKGSLLGCSIDITSAA DSEAVTYQKLVKGHAYSVTGAEEVE SSGSLQKLIRIRNPWGQVEWTGKWN DNCPSWNTVDPEVRANLTERQEDGE FWMSFSDFLRHYSRLEICNLTPDTL TCDSYKKWKLTKMDGNWRRGSTAGG CRNYPNTFWMNPQYLIKLEEEDEDD EDGERGCTFLVGLIQKHRRRQRKMG EDMHTIGFGIYEVPEELTGQTNIHL SKNFFLTTRARERSDTFINLREVLN RFKLPPGEYVLVPSTFEPHKNGDFC IRVFSEKKADYQTVDDEIEANIEEI EANEEDIGDGFRRLFAQLAGEDAEI SAFELQTILRRVLAKREDIKSDGFS IETCKIMVDMLDEDGSGKLGLKEFY ILWTKIQKYQKIYREIDVDRSGTMN SYEMRKALEEAGFKLPCQLHQVIVA RFADDELIIDFDNFVRCLVRLEILF KIFKQLDPENTGTIQLDLISWLSFS VL |
| Purity : | > 90% by SDS-PAGE |
| Storage : | Store it under sterile conditions at -20 to -80 centigrade. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles. |
| Concentration : | 1 mg/mL by BCA |
| Storage Buffer : | Sterile 50 mM Tris, pH 8.0, 100 mM NaCl, 40% Glycerol |
| Gene Name : | Capn2 calpain 2 [ Rattus norvegicus (Norway rat) ] |
| Official Symbol : | Capn2 |
| Synonyms : | Capn2; calpain 2; calpain-2 catalytic subunit; CANP 2; M-calpain; calcium-activated neutral proteinase 2; calpain 2, (m/II) large subunit; calpain II; calpain M-type; calpain-2 large subunit; millimolar-calpain; EC 3.4.22.53 |
| Gene ID : | 29154 |
| mRNA Refseq : | NM_017116 |
| Protein Refseq : | NP_058812 |
| UniProt ID : | Q07009 |
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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