Recombinant Rat Calpain 2 Capn2-2632R

Cat. No.:	Capn2-2632R
Product Overview:	Recombinant Rat Calpain 2 is expressed inE. coli.
Description:	The calpains, calcium-activated neutral proteases, are nonlysosomal, intracellular cysteine proteases. The mammalian calpains include ubiquitous, stomach-specific, and muscle-specific proteins. The ubiquitous enzymes consist of heterodimers with distinct large, catalytic subunits associated with a common small, regulatory subunit. This gene encodes the large subunit of the ubiquitous enzyme, calpain 2. Multiple heterogeneous transcriptional start sites in the 5" UTR have been reported
Source:	E. coli.
Form:	Liquid.
Formulation:	In 100 mM NaCl, 50 mM Tris-HCl, 5 mM EDTA, 5 mM β-mercaptoethanol, 40% glycerol, pH 7.8.
Molar Mass:	101000Da.
Specific Activity:	≥1500 units/mg protein.
Unit Definition:	One unit is defined as the amount of enzyme that hydrolyzes 1 pmol. Suc-leu-Leu0Val-Tyr-AMC in 1 min at 25°C.
Purity:	≥98% by SDS-PAGE.
Storage:	≤ -70oC. Ship: Dry Ice Only.

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Gene Name:	Capn2 calpain 2 [ Rattus norvegicus ]
Synonyms:	Capn2; calpain 2; CANP 2; M-calpain; calcium-activated neutral proteinase 2; calpain M-type; calpain-2 catalytic subunit; calpain-2 large subunit; millimolar-calpain; EC 3.4.22.53
Gene ID:	29154
mRNA Refseq:	NM_017116
Protein Refseq:	NP_058812
UniProt ID:	Q07009
Chromosome Location:	13q26
Pathway:	Alzheimer"s disease; Apoptosis; Focal adhesion
Function:	calcium ion binding; calcium-dependent cysteine-type endopeptidase activity; calcium-dependent cysteine-type endopeptidase activity; cytoskeletal protein binding; peptidase activity; protein binding; protein binding