Cat. No. : | Capn2-2632R |
Product Overview : | Recombinant Rat Calpain 2 is expressed inE. coli. |
Description : | The calpains, calcium-activated neutral proteases, are nonlysosomal, intracellular cysteine proteases. The mammalian calpains include ubiquitous, stomach-specific, and muscle-specific proteins. The ubiquitous enzymes consist of heterodimers with distinct large, catalytic subunits associated with a common small, regulatory subunit. This gene encodes the large subunit of the ubiquitous enzyme, calpain 2. Multiple heterogeneous transcriptional start sites in the 5" UTR have been reported |
Source : | E. coli. |
Form : | Liquid. |
Formulation : | In 100 mM NaCl, 50 mM Tris-HCl, 5 mM EDTA, 5 mM β-mercaptoethanol, 40% glycerol, pH 7.8. |
Molar Mass : | 101000Da. |
Specific Activity : | ≥1500 units/mg protein. |
Unit Definition : | One unit is defined as the amount of enzyme that hydrolyzes 1 pmol. Suc-leu-Leu0Val-Tyr-AMC in 1 min at 25°C. |
Purity : | ≥98% by SDS-PAGE. |
Storage : | ≤ -70oC. Ship: Dry Ice Only. |
Gene Name : | Capn2 calpain 2 [ Rattus norvegicus ] |
Synonyms : | Capn2; calpain 2; CANP 2; M-calpain; calcium-activated neutral proteinase 2; calpain M-type; calpain-2 catalytic subunit; calpain-2 large subunit; millimolar-calpain; EC 3.4.22.53 |
Gene ID : | 29154 |
mRNA Refseq : | NM_017116 |
Protein Refseq : | NP_058812 |
UniProt ID : | Q07009 |
Chromosome Location : | 13q26 |
Pathway : | Alzheimer"s disease; Apoptosis; Focal adhesion |
Function : | calcium ion binding; calcium-dependent cysteine-type endopeptidase activity; calcium-dependent cysteine-type endopeptidase activity; cytoskeletal protein binding; peptidase activity; protein binding; protein binding |
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