Recombinant Human B and T Lymphocyte Associated, His-tagged
Cat.No. : | BTLA-3037H |
Product Overview : | Recombinant Human BTLA protein was expressed in E.coli with His-tag at the N-terminus. The molecular weight is 32689,8 Da. |
- Specification
- Gene Information
- Related Products
Cat. No. : | BTLA-3037H |
Description : | B and T lymphocyte associated is a protein that in humans is encoded by the BTLA gene. BTLA has also been designated as CD272. BTLA expression is induced during activation of T cells, and BTLA remains expressed on Th1 cells but not Th2 cells. Like PD1 and CTLA4, BTLA interacts with a B7 homolog, B7H4. However, unlike PD-1 and CTLA-4, BTLA displays T-Cell inhibition via interaction with tumor necrosis family receptors (TNF-R), not just the B7 family of cell surface receptors. BTLA is a ligand for tumour necrosis factor (receptor) superfamily, member 14 (TNFRSF14), also known as herpes virus entry mediator (HVEM). BTLA-HVEM complexes negatively regulate T-cell immune responses. |
Sequences of amino acids : | 25-289 aa |
Formulation : | Supplied in 20 mM Tris-HCl, 0.5 M NaCl, 1 mM 2-mercaptoethanol, pH:8.0 and contains not preservatives. |
Gene Name : | BTLA B and T lymphocyte associated [ Homo sapiens ] |
Synonyms : | BTLA1; CD272; FLJ16065; MGC129743; B- and T-lymphocyte attenuator; B and T lymphocyte attenuator; B- and T-lymphocyte-associated protein |
Gene ID : | 151888 |
mRNA Refseq : | NM_181780 |
Protein Refseq : | NP_861445 |
MIM : | 607925 |
UniProt ID : | Q7Z6A9 |
Chromosome Location : | 3q13.2 |
Pathway : | Signaling in Immune system |
Function : | protein binding; receptor activity |
Products Types
◆ Recombinant Protein | ||
BTLA-610H | Recombinant Human BTLA Protein, Fc-tagged | +Inquiry |
BTLA-567H | Active Recombinant Human BTLA Protein, Fc-Avi-tagged, Biotinylated | +Inquiry |
BTLA-20H | Recombinant Human BTLA Protein (ECD), Fc-His-tagged(C-ter) | +Inquiry |
BTLA-2828H | Recombinant Human BTLA Protein, MYC/DDK-tagged | +Inquiry |
Btla-1902M | Recombinant Mouse Btla Protein, Myc/DDK-tagged | +Inquiry |
◆ Lysates | ||
BTLA-1278MCL | Recombinant Mouse BTLA cell lysate | +Inquiry |
BTLA-732CCL | Recombinant Cynomolgus BTLA cell lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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