Recombinant Mouse Thioredoxin Reductase 1, His-tagged
Cat.No. : | Txnrd1-736M |
Product Overview : | Recombinant mouse cytosolic thioredoxin with a 6-His tag is fully active with thioredoxin reductase. Mr is approximately 12,000 D. |
- Specification
- Gene Information
- Related Products
Cat. No. : | Txnrd1-736M |
Description : | This gene encodes a member of the family of pyridine nucleotide oxidoreductases. This protein reduces thioredoxins as well as other substrates, and plays a role in selenium metabolism and protection against oxidative stress. The functional enzyme is thought to be a homodimer which uses FAD as a cofactor. Each subunit contains a selenocysteine (Sec) residue which is required for catalytic activity. The selenocysteine is encoded by the UGA codon that normally signals translation termination. The 3" UTR of selenocysteine-containing genes have a common stem-loop structure, the sec insertion sequence (SECIS), that is necessary for the recognition of UGA as a Sec codon rather than as a stop signal. Alternative splicing results in several transcript variants encoding the same or different isoforms. |
Source : | E.coli. |
Purity : | Purified via immunoaffinity column chromatography, it contains no E. coli Thioredoxin-S2. |
Presentation : | 100 μg of protein, salt-free, lyophilized from 0.5% NH4CO3. |
Reconstitution : | Add 100 μL of filtered deionized water or physiological buffer to generate a 1 mg/mL solution. |
Storage : | Store the lyophilized product at 2°- 8°C. |
Gene Name : | Txnrd1 thioredoxin reductase 1 [ Mus musculus ] |
Synonyms : | Txnrd1; thioredoxin reductase 1; TR; TR1; TrxR1; thioredoxin reductase 1, cytoplasmic; TR alpha; thioredoxin reductase TR1; EC 1.8.1.9 |
Gene ID : | 50493 |
mRNA Refseq : | NM_001042513 |
Protein Refseq : | NP_001035978 |
UniProt ID : | Q9JMH6 |
Chromosome Location : | 10 C1; 10 |
Pathway : | Pyrimidine metabolism |
Function : | FAD binding; NADP or NADPH binding; oxidoreductase activity; oxidoreductase activity, acting on sulfur group of donors, NAD or NADP as acceptor; thioredoxin-disulfide reductase activity |
Products Types
◆ Recombinant Protein | ||
TXNRD1-517H | Recombinant Human TXNRD1 Protein, His-tagged | +Inquiry |
TXNRD1-24C | Recombinant C. elegans TXNRD1 Protein | +Inquiry |
Txnrd1-021R | Recombinant Rat Txnrd1 Protein | +Inquiry |
TXNRD1-22H | Recombinant Human TXNRD1 Protein | +Inquiry |
TXNRD1-6034R | Recombinant Rat TXNRD1 Protein, His (Fc)-Avi-tagged | +Inquiry |
◆ Lysates | ||
TXNRD1-1866HCL | Recombinant Human TXNRD1 cell lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
Inquiry
0
Inquiry Basket