"RPA2" Related Products

Expand

Recombinant Human Replication Protein A2, 32kDa, His-tagged

Cat. No.: RPA2-2852H
Product Overview: Recombinant human RPA2 protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques. MW =31.7 kDa (293aa) confirmed by MALDI-TOF.
Description: Replication Protein A (RPA) is a single stranded DNA binding protein. Human RPA is a heterotrimeric protein containing subunits of 14, 32 and 70kDa. This protein complex is highly conserved in eukaryotes and is essential in DNA replication, homologous recombination and nucleotide excision repair. The C-terminus of RPA2 can specfically intereact with the DNA repair enzyme UNG2 and repair factors XPA and Rad52, each of which functions in a different repair pathway. In addition, this protein binds specifically to the SH2 domain of Stat3 in vivo, and overexpression of RPA2 corresponds to the augmented growth factor-stimulated tyrosine phosphorylation and transcription activities of Stat3.
Source: E.coli.
Amino Acid Sequence: MGSSHHHHHH SSGLVPRGSH MGSMWNSGFE SYGSSSYGGA GGYTQSPGGF GSPAPSQAEK KSRARAQHIV PCTISQLLSA TLVDEVFRIG NVEISQVTIV GIIRHAEKAP TNIVYKIDDM TAAPMDVRQW VDTDDTSSEN TVVPPETYVK VAGHLRSFQN KKSLVAFKIM PLEDMNEFTT HILEVINAHM VLSKANSQPS AGRAPISNPG MSEAGNFGGN SFMPANGLTV AQNQVLNLIK ACPRPEGLNF QDLKNQLKHM SVSSIKQAVD FLSNEGHIYS TVDDDHFKST DAE
Form: Liquid. In 20mM Tris-HCl buffer (pH 8.0) containing 10% glycerol, 2mM DTT, 0.1M NaCl.
Purity: > 85 % by SDS – PAGE.
Concentration: 0.5 mg/ml (determined by Bradford assay).
Storage: Can be stored at +4°C short term (1-2 weeks). For long term storage, aliquot and store at -20°C or -70°C. Avoid repeated freezing and thawing cycles.
Gene Name: RPA2 replication protein A2, 32kDa [ Homo sapiens ]
Synonyms: RPA2; replication protein A2, 32kDa; REPA2; RPA32; replication protein A 32 kDa subunit; RP-A p32; RP-A p34; RF-A protein 2; OTTHUMP00000004010; replication factor A protein 2; replication protein A 34 kDa subunit; RPA34; replication protein A2 (32kD)
Gene ID: 6118
mRNA Refseq: NM_002946
Protein Refseq: NP_002937
MIM: 179836
UniProt ID: P15927
Chromosome Location: 1p35
Pathway: DNA replication; Homologous recombination; Mismatch repair; Nucleotide excision repair
Function: nucleic acid binding; protein binding; single-stranded DNA binding

Online Inquiry

Note: There will be extra charge for optional service!

Please input "biomart" as verification code. Please review Creative BioMart's privacy policy for more information

Optional requirements on this protein    +Expand

Price Inquiry

Welcome! For price inquiries, please feel free to contact us through the form below. We will get back to you as soon as possible.