Recombinant Human WD Repeat Domain 4, T7-tagged

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Recombinant Human WD Repeat Domain 4, T7-tagged

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Cat. No. : WDR4-847H
Product Overview : Recombinant Human WDR4 was produced in E.coli with a T7 tag at N-terminus. MW = 45490 Da (1-266 aa).
Description : tRNA (guanine-N(7)-)-methyltransferase subunit WDR4 is an enzyme that in humans is encoded by the WDR4 gene. This gene encodes a member of the WD repeat protein family. WD repeats are minimally conserved regions of approximately 40 amino acids typically bracketed by gly-his and trp-asp (GH-WD), which may facilitate formation of heterotrimeric or multiprotein complexes. Members of this family are involved in a variety of cellular processes, including cell cycle progression, signal transduction, apoptosis, and gene regulation. This gene is excluded as a candidate for a form of nonsyndromic deafness (DFNB10), but is still a candidate for other disorders mapped to 21q22.3 as well as for the development of Down syndrome phenotypes. Two transcript variants encoding the same protein have been found for this gene.
Source : E.coli.
Form : 10 mM Tris. pH 8.0. 0.1% Triton X-100. 0.002% NaN3.
Purity : 90%.
Clonality : N/A.
Applications : MS. SDS.
Gene Name : WDR4 WD repeat domain 4 [ Homo sapiens ]
Synonyms : WDR4 WD repeat domain 4; TRM82; tRNA (guanine-N(7)-)-methyltransferase subunit WDR4; WD repeat-containing protein 4
Gene ID : 10785
mRNA Refseq : NM_018669
Protein Refseq : NP_061139
MIM : 605924
UniProt ID : P57081
Chromosome Location : 21q22.3
Function : protein binding; contributes_to tRNA (guanine-N7-)-methyltransferase activity
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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