Recombinant Human Chemokine (C-C Motif) Ligand 13, His-tagged

• Cat.No.: CCL13-2792H
• Product Overview: Recombinant human CCL13 protein (24-98aa), fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques.

Specification

• Species: Human
• Source: E.coli
• Tag: His
• Protein Length: 24-98 a.a.
• Description: CCL13 is a small cytokine belonging to the CC chemokine family that is also known as thymus and activation regulated chemokine (TARC). This protein induces chemotaxis in monocytes, eosinophils, T lymphocytes, and basophils by binding cell surface G-protein linked chemokine receptors such as CCR2, CCR3 and CCR5. It can be induced by the inflammatory cytokines interleukin-1 and TNF-α.
• Sequences: MGSSHHHHHH SSGLVPRGSH MQPDALNVPS TCCFTFSSKK ISLQRLKSYV ITTSRCPQKA VIFRTKLGKE ICADPKEKWV QNYMKHLGRK AHTLKT.
• Form: Liquid. In 20 mM Tris-HCl buffer (pH7.4) containing 0.1M Nacl, 1mM DTT, 10% glycerol.
• Molecular Weight: 10.8 kDa (96aa),confirmed by MALDI-TOF.
• Purity: > 90% by SDS – PAGE.
• Concentration: 0.25 mg/ml (determined by Bradford assay).
• Storage: Can be stored at +4°C short term (1-2 weeks). For long term storage, aliquot and store at -20°C or -70°C. Avoid repeated freezing and thawing cycles.

Gene Information

• Gene Name: CCL13 chemokine (C-C motif) ligand 13 [ Homo sapiens ]
• Synonyms:
  CCL13; chemokine (C-C motif) ligand 13; C-C motif chemokine 13; CK-beta-10; monocyte chemoattractant protein 4; monocyte chemotactic protein 4; new CC chemokine 1; small inducible cytokine subfamily A (Cys-Cys), member 13; small-inducible cytokine A13; NCC1; CKb10; MCP-4; NCC-1; SCYL1; SCYA13; MGC17134
• Gene ID: 6357
• mRNA Refseq: NM_005408
• Protein Refseq: NP_005399
• MIM: 601391
• UniProt ID: Q99616
• Chromosome Location: 17q11.2
• Pathway: Chemokine signaling pathway; Cytokine-cytokine receptor interaction; NOD-like receptor signaling pathway
• Function: chemokine activity; receptor binding; signal transducer activity