"IFNA2" Related Products

Recombinant Human Interferon, Alpha 2

Cat. No.: IFNA2-91H
Product Overview: Recombinant Human Interferon, Alpha 2 was expressed inPseudomonas putida. MW = 19.2 kDa.
Description: Interferon-α (INF-α), also known as leukocyte interferon, comprises a grope of related but distinct proteins that share over 95 % amino acid sequence homology. They are members of the type I interferon family which share a common cell surface receptor composed of two subunits, 100 kDa ligand-binding subunit (INF-αR1) and a 125 kDa subunit (INF-αR2) that is involved both in ligand binding and signal transduction. INF-α has both anti-viral and immunomodulatory activities on target cells.
Source: Pseudomonas putida.
Purity: >98% determined by HPLC and PAGE.
Form: lyophilised with carrier.
Sterilized: Yes.
Biological Activity: >2.5 x 10E+8 unit/mg was determined in the cytopathic effect inhibition assay using human diploid fibroblast cells with vesicular stomatitis virus (VSV). A cytopathic effect of 50% was produced with 1 unit/ml interferon. The units are determined according to the international reference standard provided by WHO.
Contaminations: protein <2% (HPLC), DNA <50pg/mg of protein.
Storage: -70°C.
Gene Name: IFNA2 interferon, alpha 2 [ Homo sapiens ]
Synonyms: IFNA2; interferon, alpha 2; Interferon, alpha-2;; IFNA; INFA2; MGC125764; MGC125765; Interferon alpha A; Alpha-2a interferon; Interferon alpha 2b; OTTHUMP00000021143; Interferon alpha-A; LeIF A
Gene ID: 3440
mRNA Refseq: NM_000605
Protein Refseq: NP_000596
MIM: 147562
UniProt ID: P01563
Chromosome Location: 9p22
Pathway: Antigen processing and presentation; Autoimmune thyroid disease; Cytokine-cytokine receptor interaction; Jak-STAT signaling pathway; Natural killer cell mediated cytotoxicity; RIG-I-like receptor signaling pathway; Regulation of autophagy; Toll-like receptor signaling pathway
Function: cytokine activity; interferon-alpha/beta receptor binding

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