GMP Recombinant Human NOG Protein
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|Product Overview :||Recombinant Human NOG, Gln28-Cys232, Fused with Human IgG1 at C-terminal was produced in NS0 cell under cGMP guidelines.|
|Form :||Lyophilized from a 0.2 μm filtered solution in PBS.|
|Bio-activity :||Measured by its ability to inhibit BMP-4-induced alkaline phosphatase production by ATDC5 mouse chondrogenic cells. The ED50 for this effect is 0.1-0.4 μg/mL in the presence of 30 ng/mL of Recombinant Human BMP‑4.|
|Molecular Mass :||Predicted Molecular Mass: 49.6 (monomer) kDa
SDS-PAGE: 58-62 kDa, reducing conditions
130-135 kDa, non-reducing conditions
|Endotoxin :||<0.10 EU per 1 μg of the protein by the LAL method.|
|Purity :||>90%, by SDS-PAGE with silver staining, under reducing conditions.|
|Storage :||Avoid repeated freeze-thaw cycles.
12 months, -20 to -70 centigrade as supplied.
1 month, 2 to 8 centigrade under sterile conditions after reconstitution.
3 months, -20 to -70 centigrade under sterile conditions after reconstitution.
|Reconstitution :||Reconstitute at 100 μg/mL in PBS.|
|Quality Statement :||Our GMP proteins are produced according to relevant sections of the following documents: WHO TRS, No. 822, 1992 Annex 1, Good Manufacturing Practices for Biological Products; USP Chapter 1043, Ancillary Materials for Cell, Gene and Tissue-Engineered Products and USP Chapter 92, Growth Factors and Cytokines Used in Cell Therapy Manufacturing.|
|Shipping :||The product is shipped at ambient temperature. Upon receipt, store it immediately at the recommended temperature.|
|Gene Name :||NOG noggin [ Homo sapiens ]|
|Official Symbol :||NOG|
|Synonyms :||NOG; noggin; symphalangism 1 (proximal); SYM1; SYNS1;|
|Gene ID :||9241|
|mRNA Refseq :||NM_005450|
|Protein Refseq :||NP_005441|
|UniProt ID :||Q13253|
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