GMP Recombinant Human NOG Protein NOG-117HG

GMP Recombinant Human NOG Protein


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GMP Recombinant Human NOG Protein

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Cat.No. : NOG-117HG
Product Overview : Recombinant Human NOG, Gln28-Cys232, Fused with Human IgG1 at C-terminal was produced in NS0 cell under cGMP guidelines.
Source : NS0
Species : Human
Tag : Fc
Form : Lyophilized from a 0.2 μm filtered solution in PBS.
Bio-activity : Measured by its ability to inhibit BMP-4-induced alkaline phosphatase production by ATDC5 mouse chondrogenic cells. The ED50 for this effect is 0.1-0.4 μg/mL in the presence of 30 ng/mL of Recombinant Human BMP‑4.
Molecular Mass : Predicted Molecular Mass: 49.6 (monomer) kDa
SDS-PAGE: 58-62 kDa, reducing conditions
130-135 kDa, non-reducing conditions
Endotoxin : <0.10 EU per 1 μg of the protein by the LAL method.
Purity : >90%, by SDS-PAGE with silver staining, under reducing conditions.
Storage : Avoid repeated freeze-thaw cycles.
12 months, -20 to -70 centigrade as supplied.
1 month, 2 to 8 centigrade under sterile conditions after reconstitution.
3 months, -20 to -70 centigrade under sterile conditions after reconstitution.
Reconstitution : Reconstitute at 100 μg/mL in PBS.
Quality Statement : Our GMP proteins are produced according to relevant sections of the following documents: WHO TRS, No. 822, 1992 Annex 1, Good Manufacturing Practices for Biological Products; USP Chapter 1043, Ancillary Materials for Cell, Gene and Tissue-Engineered Products and USP Chapter 92, Growth Factors and Cytokines Used in Cell Therapy Manufacturing.
Shipping : The product is shipped at ambient temperature. Upon receipt, store it immediately at the recommended temperature.
Gene Name : NOG noggin [ Homo sapiens ]
Official Symbol : NOG
Synonyms : NOG; noggin; symphalangism 1 (proximal); SYM1; SYNS1;
Gene ID : 9241
mRNA Refseq : NM_005450
Protein Refseq : NP_005441
MIM : 602991
UniProt ID : Q13253

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