Human β-Amyloid (1-42)
Cat.No. : | APP-001H |
Product Overview : | CAS No. 107761-42-2 Solubility: Soluble in water |
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Description : | This peptide is well suited to the quantitative determination of A 42 peptide. Alzheimer’s disease (AD) is characterized by the presence of extracellular plaques and intracellular neurofibrillary tangles (NFTs) in the brain. The major protein component of these plaques is beta amyloid peptide (A), a 40- to 43- amino-acid peptide cleaved from amyloid precursor protein by secretase (BACE) and a putative (gamma) secretase. Increased release of the ‘longer forms’ of A peptide, A 42 and A 43, which have a greater tendency to aggregate than A 40, occurs in individuals expressing certain genetic mutations, expressing certain ApoE alleles or may other, still undiscovered factors. |
Source : | Synthetic |
Species : | Human |
Molecular Mass : | 4514.1 Da |
AA Sequence : | Sequence: Asp-Ala-Glu-Phe-Arg-His-Asp-Ser-Gly-Tyr-Glu-Val-His-His-Gln-Lys-Leu-Val-Phe-Phe-Ala-Glu-Asp-Val-Gly-Ser-Asn-Lys-Gly-Ala-Ile-Ile-Gly-Leu-Met-Val-Gly-Gly-Val-Val-Ile-Ala Sequence Shortening: DAEFRHDSGYEVHHQKLVFFAEDVGSNKGAIIGLMVGGVVIA |
Purity : | > 95% |
Storage : | Store at -20 centigrade. |
Gene Name : | APP |
Official Symbol : | APP amyloid beta precursor protein [ Homo sapiens (human) ] |
Synonyms : | APP; amyloid beta precursor protein; AAA; AD1; PN2; ABPP; APPI; CVAP; ABETA; PN-II; preA4; CTFgamma; amyloid-beta A4 protein; alzheimer disease amyloid protein; amyloid beta (A4) precursor protein; amyloid beta A4 protein; amyloid precursor protein; beta-amyloid peptide; beta-amyloid peptide(1-40); beta-amyloid peptide(1-42); beta-amyloid precursor protein; cerebral vascular amyloid peptide; peptidase nexin-II; protease nexin-II; testicular tissue protein Li 2 |
Gene ID : | 351 |
mRNA Refseq : | NM_000484 |
Protein Refseq : | NP_000475 |
MIM : | 104760 |
UniProt ID : | P05067 |
Products Types
◆ Recombinant Protein | ||
APP-2488H | Recombinant Human APP Protein, His (Fc)-Avi-tagged | +Inquiry |
APP-230H | Recombinant Human APP Protein, His-tagged | +Inquiry |
App-232R | Recombinant Rat App Protein, His&GST-tagged | +Inquiry |
APP-2551H | Recombinant Human APP protein(672-711 aa) | +Inquiry |
APP-387R | Recombinant Rat APP Protein, His (Fc)-Avi-tagged | +Inquiry |
◆ Lysates | ||
APP-3087HCL | Recombinant Human APP cell lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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