Human ATG16L1 Knockdown Cell Lysate

• Cat.No.: ATG16L1-001HKCL
• Product Overview: WB-validated ATG16L1 Knockdown Cell Lysate

Specification

• Species: Human
• Source: 293T
• Tag: Non
• Description: The protein encoded by this gene is part of a large protein complex that is necessary for autophagy, the major process by which intracellular components are targeted to lysosomes for degradation. Defects in this gene are a cause of susceptibility to inflammatory bowel disease type 10 (IBD10). Several transcript variants encoding different isoforms have been found for this gene.
• Form: Cell-Tissue Lysis buffer
• Molecular Mass: 68 kDa
• Notes: Instruction of use: This knockdown cell lysate should be paired with wild-type 293T cell lysate for use. For Western blotting, we recommend running wild-type and knockdown lysates on the same gel, and loading each well with equal volume and equal amount of total proteins.
• Storage: Store at -20 centigrade for two years.
• Concentration: Lot-specific
• Shipping: Blue Ice
• Components: 1 vial of 100 μg WT 293T cell lysate 1 vial of 100 μg ATG16L1 KD 293T cell lysate
• Lysate QC: RT-qPCR; Western Blotting (WB)

Gene Information

• Gene Name: ATG16L1 autophagy related 16 like 1 [ Homo sapiens (human) ]
• Official Symbol: ATG16L1
• Synonyms: ATG16L1; ATG16 autophagy related 16-like 1 (S. cerevisiae); APG16 autophagy 16 like (S. cerevisiae), APG16L, ATG16 autophagy related 16 like (S. cerevisiae), ATG16L; autophagy-related protein 16-1; ATG16A; FLJ10035; WDR30; APG16L beta; WD repeat domain 30; IBD10; APG16L; ATG16L; FLJ00045; FLJ10828; FLJ22677
• Gene ID: 55054
• mRNA Refseq: NM_001190266
• Protein Refseq: NP_001177195
• MIM: 610767
• UniProt ID: Q676U5