Human EXOG Knockdown Cell Lysate

• Cat.No.: EXOG-161HKCL
• Product Overview: WB-validated EXOG Knockdown HeLa Cell Lysate

Specification

• Species: Human
• Source: HeLa
• Tag: Non
• Description: This gene encodes an endo/exonuclease with 5'-3' exonuclease activity. The encoded enzyme catalyzes the hydrolysis of ester linkages at the 5' end of a nucleic acid chain. This enzyme is localized to the mitochondria and may play a role in programmed cell death. Alternatively spliced transcript variants have been described. A pseudogene exists on chromosome 18.
• Form: Cell-Tissue Lysis buffer
• Molecular Mass: 41 kDa
• Notes: Instruction of use: This knockdown cell lysate should be paired with wild-type HeLa cell lysate for use. For Western blotting, we recommend running wild-type and knockdown lysates on the same gel, and loading each well with equal volume and equal amount of total proteins.
• Storage: Store at -20 centigrade for two years.
• Concentration: Lot-specific
• Shipping: Blue Ice
• Components: 1 vial of 100 μg WT HeLa cell lysate 1 vial of 100 μg EXOG KD HeLa cell lysate
• Protein Families: Druggable Genome, Transmembrane
• Protein Pathways: Apoptosis
• Lysate QC: RT-qPCR; Western Blotting (WB)

Gene Information

• Gene Name: EXOG endo/exonuclease (5-3), endonuclease G-like [ Homo sapiens (human) ]
• Official Symbol: EXOG
• Synonyms: EXOG; endo/exonuclease (5-3), endonuclease G-like; ENDOGL1, ENDOGL2, endonuclease G like 1, endonuclease G like 2; nuclease EXOG, mitochondrial; ENGL; ENGL a; ENGL b; endo G-like 1; endonuclease G-like 1; endonuclease G-like 2; ENGLA; ENGLB; ENGL-a; ENGL-b; ENDOGL1; ENDOGL2; MGC125944; MGC125945
• Gene ID: 9941
• mRNA Refseq: NM_001145464
• Protein Refseq: NP_001138936
• MIM: 604051
• UniProt ID: Q9Y2C4