Human PRKDC Knockdown Cell Lysate

• Cat.No.: PRKDC-280HKCL
• Product Overview: WB-validated PRKDC Knockdown HeLa Cell Lysate

Specification

• Species: Human
• Source: HeLa
• Tag: Non
• Description: This gene encodes the catalytic subunit of the DNA-dependent protein kinase (DNA-PK). It functions with the Ku70/Ku80 heterodimer protein in DNA double strand break repair and recombination. The protein encoded is a member of the PI3/PI4-kinase family.
• Form: Cell-Tissue Lysis buffer
• Molecular Mass: 469 kDa
• Notes: Instruction of use: This knockdown cell lysate should be paired with wild-type HeLa cell lysate for use. For Western blotting, we recommend running wild-type and knockdown lysates on the same gel, and loading each well with equal volume and equal amount of total proteins.
• Storage: Store at -20 centigrade for two years.
• Concentration: Lot-specific
• Shipping: Blue Ice
• Components: 1 vial of 100 μg WT HeLa cell lysate 1 vial of 100 μg PRKDC KD HeLa cell lysate
• Protein Families: Druggable Genome, Protein Kinase
• Protein Pathways: Cell cycle, Non-homologous end-joining
• Lysate QC: RT-qPCR; Western Blotting (WB)

Gene Information

• Gene Name: PRKDC protein kinase, DNA-activated, catalytic polypeptide [ Homo sapiens (human) ]
• Official Symbol: PRKDC
• Synonyms: PRKDC; protein kinase, DNA-activated, catalytic polypeptide; HYRC, HYRC1; DNA-dependent protein kinase catalytic subunit; DNA PKcs; DNAPK; DNPK1; p350; XRCC7; p460; DNA-PK catalytic subunit; hyper-radiosensitivity of murine scid mutation, complementing 1; HYRC; HYRC1; DNA-PKcs
• Gene ID: 5591
• mRNA Refseq: NM_001081640
• Protein Refseq: NP_001075109
• MIM: 600899
• UniProt ID: P78527