Recombinant Human PRKDC Protein
Cat.No. : | PRKDC-859H |
Product Overview : | Recombinant Human PRKDC was expressed in Insect cells. |
- Specification
- Gene Information
- Related Products
Description : | DNA-PK is a heterotrimeric, DNA-dependent protein kinase that initiates signalling cascades in response to DNA damage. DNA-PK is an atypical kinase, closely related to the PI3 kinases, and is often potently inhibited by small molecules designed to target PI3 kinases. |
Source : | Insect cells |
Species : | Human |
Form : | Frozen |
Molecular Mass : | 600 kDa |
Applications : | Kinase Assay |
Storage : | Kinase proteins are shipped on dry ice and should be stored at -80 centigrade |
Gene Name : | PRKDC protein kinase, DNA-activated, catalytic polypeptide [ Homo sapiens ] |
Official Symbol : | PRKDC |
Synonyms : | PRKDC; protein kinase, DNA-activated, catalytic polypeptide; HYRC, HYRC1; DNA-dependent protein kinase catalytic subunit; DNA PKcs; DNAPK; DNPK1; p350; XRCC7; p460; DNA-PK catalytic subunit; hyper-radiosensitivity of murine scid mutation, complementing 1; HYRC; HYRC1; DNA-PKcs; |
Gene ID : | 5591 |
mRNA Refseq : | NM_001081640 |
Protein Refseq : | NP_001075109 |
MIM : | 600899 |
UniProt ID : | P78527 |
Products Types
◆ Recombinant Protein | ||
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Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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- Q&As
- Reviews
Q&As (5)
Ask a questionPRKDC consists of an N-terminal helical domain, a circular cradle domain containing multiple HEAT repeats and a large number of conserved phosphorylation clusters, and a C-terminal domain containing a highly conserved kinase architecture.
PRKDC is involved in lymphocyte development, antibody V(D)J recombination, immunoglobulin and T-cell receptor gene assembly, and the establishment of the central immune tolerance system.
PRKDC is relevant to the study of breast cancer, gastric cancer, liver cancer and other diseases.
Lack of PRKDC gene function will lead to symptoms of immunodeficiency.
PRKDC is usually connected to His, and we will adapt it to your needs!
Customer Reviews (3)
Write a reviewThe product was kept in perfect condition and delivered on time so that I got the perfect product in the shortest time possible.
The purchased antibodies were very sensitive and helped me to get satisfactory experimental results.
Customer service contacted me in a timely manner and helped me solve a lot of problems that arose in my experiments.
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