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Recombinant Human PRKDC Protein

Cat.No. : PRKDC-859H
Product Overview : Recombinant Human PRKDC was expressed in Insect cells.
  • Specification
  • Gene Information
  • Related Products
Description : DNA-PK is a heterotrimeric, DNA-dependent protein kinase that initiates signalling cascades in response to DNA damage. DNA-PK is an atypical kinase, closely related to the PI3 kinases, and is often potently inhibited by small molecules designed to target PI3 kinases.
Source : Insect cells
Species : Human
Form : Frozen
Molecular Mass : 600 kDa
Applications : Kinase Assay
Storage : Kinase proteins are shipped on dry ice and should be stored at -80 centigrade
Gene Name : PRKDC protein kinase, DNA-activated, catalytic polypeptide [ Homo sapiens ]
Official Symbol : PRKDC
Synonyms : PRKDC; protein kinase, DNA-activated, catalytic polypeptide; HYRC, HYRC1; DNA-dependent protein kinase catalytic subunit; DNA PKcs; DNAPK; DNPK1; p350; XRCC7; p460; DNA-PK catalytic subunit; hyper-radiosensitivity of murine scid mutation, complementing 1; HYRC; HYRC1; DNA-PKcs;
Gene ID : 5591
mRNA Refseq : NM_001081640
Protein Refseq : NP_001075109
MIM : 600899
UniProt ID : P78527

For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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Q&As (5)

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What is the structure domain of PRKDC? 11/10/2022

PRKDC consists of an N-terminal helical domain, a circular cradle domain containing multiple HEAT repeats and a large number of conserved phosphorylation clusters, and a C-terminal domain containing a highly conserved kinase architecture.

What are the biological functions of PRKDC? 07/14/2022

PRKDC is involved in lymphocyte development, antibody V(D)J recombination, immunoglobulin and T-cell receptor gene assembly, and the establishment of the central immune tolerance system.

PRKDC is closely related to the study of those diseases? 04/12/2022

PRKDC is relevant to the study of breast cancer, gastric cancer, liver cancer and other diseases.

What are the consequences of PRKDC gene deletion? 01/03/2022

Lack of PRKDC gene function will lead to symptoms of immunodeficiency.

What tag is PRKDC usually connected to? 11/24/2021

PRKDC is usually connected to His, and we will adapt it to your needs!

Customer Reviews (3)

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Reviews
09/24/2021

    The product was kept in perfect condition and delivered on time so that I got the perfect product in the shortest time possible.

    05/10/2021

      The purchased antibodies were very sensitive and helped me to get satisfactory experimental results.

      12/30/2020

        Customer service contacted me in a timely manner and helped me solve a lot of problems that arose in my experiments.

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