Recombinant Active Human MUC1 Protein, Fc-His-tagged(C-ter)
Cat.No. : | MUC1-244H |
Product Overview : | Recombinant Active Human MUC1 Protein with Fc-His tag (C-ter) was expressed in HEK293. |
- Specification
- Gene Information
- Related Products
Description : | This gene encodes a membrane-bound protein that is a member of the mucin family. Mucins are O-glycosylated proteins that play an essential role in forming protective mucous barriers on epithelial surfaces. These proteins also play a role in intracellular signaling. This protein is expressed on the apical surface of epithelial cells that line the mucosal surfaces of many different tissues including lung, breast stomach and pancreas. This protein is proteolytically cleaved into alpha and beta subunits that form a heterodimeric complex. The N-terminal alpha subunit functions in cell-adhesion and the C-terminal beta subunit is involved in cell signaling. Overexpression, aberrant intracellular localization, and changes in glycosylation of this protein have been associated with carcinomas. This gene is known to contain a highly polymorphic variable number tandem repeats (VNTR) domain. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Feb 2011] |
Source : | HEK293 |
Species : | Human |
Tag : | Fc-His(C-ter) |
Form : | Powder |
Bio-activity : | Measured by its ability to increase beta-catenin levels in the cytoplasm and nucleus of HCT116 human colon adenocarcinoma cells. 0.01-1 ng/mL of Recombinant Human MUC-1 can effectively increase beta-catenin levels. |
Protein Length : | Met1-Gly167 |
Endotoxin : | Endotoxin level is less than 0.1 EU/μg of the protein, as determined by the LAL test. |
Purity : | > 97% (by SDS-PAGE) |
Applications : | FuncSt, SDS-PAGE |
Notes : | For laboratory research only, not for drug, diagnostic or other use. |
Storage : | Lyophilized protein should be stored at -20°C or -80°C. After reconstitution, aliquot and store at -20°C for up to one month, at 2-8°C for up to one week. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. |
Storage Buffer : | PBS (pH 7.4) |
Reconstitution : | Reconstitute to a concentration of 0.1-0.5 mg/ml in sterile distilled water. |
Gene Name : | MUC1 mucin 1, cell surface associated [ Homo sapiens ] |
Official Symbol : | MUC1 |
Synonyms : | MUC1; mucin 1, cell surface associated; mucin 1, transmembrane , PUM; mucin-1; CD227; PEM; episialin; DF3 antigen; H23 antigen; krebs von den Lungen-6; mucin 1, transmembrane; tumor-associated mucin; carcinoma-associated mucin; polymorphic epithelial mucin; peanut-reactive urinary mucin; tumor associated epithelial mucin; breast carcinoma-associated antigen DF3; tumor-associated epithelial membrane antigen; EMA; PUM; KL-6; MAM6; PEMT; H23AG; MUC-1; MUC-1/X; MUC1/ZD; MUC-1/SEC; |
Gene ID : | 4582 |
mRNA Refseq : | NM_001018016 |
Protein Refseq : | NP_001018016 |
MIM : | 158340 |
UniProt ID : | P15941 |
Products Types
◆ Recombinant Protein | ||
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MUC1-2661H | Recombinant Human MUC1 protein(31-150 aa), C-His-tagged | +Inquiry |
MUC1-0036H | Recombinant Human MUC1 Protein | +Inquiry |
MUC1-386H | Recombinant Human MUC1 Protein, Fc-tagged | +Inquiry |
MUC1-18H | Active Recombinant Human MUC1 Protein, Fc-tagged, Alexa Fluor® 647 conjugated | +Inquiry |
◆ Native Protein | ||
MUC1-135B | Native Bovine MUC1 Protein | +Inquiry |
MUC1-376H | Active Native Human MUC1 | +Inquiry |
MUC1-4770H | Active Native Human MUC1 Protein | +Inquiry |
◆ Lysates | ||
MUC1-1980HCL | Recombinant Human MUC1 cell lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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