Recombinant Chicken CSF2 protein

• Cat.No.: CSF2-16C
• Product Overview: Recombinant Chicken CSF2 was expressed in Yeast. Chicken GM-CSF was produced in yeast and therefore does not have endotoxin, is naturally folded, and post-translationally modified.

Specification

• Description: Granulocyte-macrophage colony-stimulating factor (GM-CSF) is a protein secreted by macrophages, T cells, mast cells, NK cells, endothelial cells and fibroblasts. GM-CSF stimulates stem cells to produce granulocytes (neutrophils, eosinophils, and basophils) and monocytes. Granulocyte macrophage–colony stimulating factor (GM-CSF) is secreted in response to inflammatory stimuli such as LPS, IL-1, and TNF-α by a variety of different cells, including endothelium, fibroblasts, muscle cells, and macrophages, and by activated T cells. GM-CSF is glycosylated in its mature form.
• Source: Yeast
• Species: Chicken
• Molecular Mass: Has a predicted molecular weight of 14.2 kDa.
• AA Sequence: TTTYSCCYKV YTILEEITSH LESTAATAGL SSVPMDIRDK TCLRNNLKTF IESLKTNGTE EESGIVFQLN RVHECERLFS NITPTPQVPD KECRTAQVSR EKFKEALKTF FIYLSDVLPE EKDCI (125)
• Applications: The Chicken GM-CSF protein can be used in cell culture, as an GM-CSF ELISA Standard, and as a Western Blot Control.
• Publication:
  Isolation and culture of chicken bone marrow-derived CD34+ hematopoietic stem and progenitor cells and induced differentiation to myeloid cells (2023)

Gene Information

• Gene Name: CSF2 colony stimulating factor 2 (granulocyte-macrophage) [ Gallus gallus ]
• Official Symbol: CSF2
• Synonyms: GMCSF; GM-CSF; granulocyte-macrophage colony-stimulating factor
• Gene ID: 416325
• mRNA Refseq: NM_001007078
• Protein Refseq: NP_001007079
• Chromosome Location: chromosome: 13
• Pathway: Cytokine-cytokine receptor interaction, organism-specific biosystem; Jak-STAT signaling pathway, organism-specific biosystem; Salmonella infection, organism-specific biosystem