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Recombinant Chicken CSF2 protein

Cat.No. : CSF2-16C
Product Overview : Recombinant Chicken CSF2 was expressed in Yeast. Chicken GM-CSF was produced in yeast and therefore does not have endotoxin, is naturally folded, and post-translationally modified.
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Description : Granulocyte-macrophage colony-stimulating factor (GM-CSF) is a protein secreted by macrophages, T cells, mast cells, NK cells, endothelial cells and fibroblasts. GM-CSF stimulates stem cells to produce granulocytes (neutrophils, eosinophils, and basophils) and monocytes. Granulocyte macrophage–colony stimulating factor (GM-CSF) is secreted in response to inflammatory stimuli such as LPS, IL-1, and TNF-α by a variety of different cells, including endothelium, fibroblasts, muscle cells, and macrophages, and by activated T cells. GM-CSF is glycosylated in its mature form.
Source : Yeast
Species : Chicken
Molecular Mass : Has a predicted molecular weight of 14.2 kDa.
AA Sequence : TTTYSCCYKV YTILEEITSH LESTAATAGL SSVPMDIRDK TCLRNNLKTF IESLKTNGTE EESGIVFQLN RVHECERLFS NITPTPQVPD KECRTAQVSR EKFKEALKTF FIYLSDVLPE EKDCI (125)
Applications : The Chicken GM-CSF protein can be used in cell culture, as an GM-CSF ELISA Standard, and as a Western Blot Control.
Tag : Non
Publication :
Isolation and culture of chicken bone marrow-derived CD34+ hematopoietic stem and progenitor cells and induced differentiation to myeloid cells (2023)
Gene Name : CSF2 colony stimulating factor 2 (granulocyte-macrophage) [ Gallus gallus ]
Official Symbol : CSF2
Synonyms : GMCSF; GM-CSF; granulocyte-macrophage colony-stimulating factor
Gene ID : 416325
mRNA Refseq : NM_001007078
Protein Refseq : NP_001007079
Chromosome Location : chromosome: 13
Pathway : Cytokine-cytokine receptor interaction, organism-specific biosystem; Jak-STAT signaling pathway, organism-specific biosystem; Salmonella infection, organism-specific biosystem

Not For Human Consumption!

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Customer Reviews (3)

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Reviews
01/15/2022

    The product's adherence to regulatory standards aligned with our lab's commitment to responsible and transparent research.

    07/27/2021

      The manufacturer's commitment to meeting regulatory requirements demonstrated its dedication to ethical research practices.

      05/19/2019

        Compliance with industry standards minimized potential roadblocks in securing approvals for our experiments.

        Q&As (7)

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        How conserved is the sequence of CSF2 among different species? 05/15/2021

        The sequence of CSF2 is moderately conserved across different species.

        What is the typical length of CSF2? 01/30/2021

        The length of CSF2 protein varies but is typically around 144 amino acids.

        What is the main biological function of CSF2? 05/01/2019

        The primary function of CSF2 is to regulate the production and differentiation of white blood cells.

        In what tissues or cells is CSF2 commonly expressed? 02/03/2019

        CSF2 is often expressed in immune cells, specifically in macrophages, T cells, and endothelial cells.

        What does CSF2 stand for? 07/10/2018

        CSF2 stands for Colony Stimulating Factor 2.

        Is CSF2 associated with any specific diseases or conditions? 03/17/2018

        CSF2 dysregulation has been linked to autoimmune diseases and inflammatory disorders.

        Which cellular functions are associated with CSF2? 02/20/2017

        CSF2 is involved in the stimulation of stem cells to produce granulocytes and monocytes.

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