Recombinant Chicken FAP Protein, K30-E759, N-His tagged

• Cat.No.: FAP-4123C
• Product Overview: Recombinant Chicken FAP protein (K30-E759) with N-His tag was expressed in HEK293.

Specification

• Description: The protein encoded by this gene is a homodimeric integral membrane gelatinase belonging to the serine protease family. It is selectively expressed in reactive stromal fibroblasts of epithelial cancers, granulation tissue of healing wounds, and malignant cells of bone and soft tissue sarcomas. This protein is thought to be involved in the control of fibroblast growth or epithelial-mesenchymal interactions during development, tissue repair, and epithelial carcinogenesis. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
• Source: HEK293
• Species: Chicken
• Tag: N-His
• Protein length: K30-E759
• Molecular Mass: 85 kDa
• AA Sequence: HHHHHHHHKVVTTVDGPRALTLDDY LNGNFQYKTYFPYWVSDSEYLHQNQ EDDIILFNVDMNYLTTIMTNSTMKQ VNASNYVMSSDKYFIALESNYSKLW RYSYTASYHIYDLIYGGFVTENQLP HKIQYISWSPVGHKLAYVYQNNIYL KQSPREAPIKLTSDGKENEIFNGIP DWVYEEEMLATKYALWWSPSGKYLA YVQFNDSDIPVIEYSYFGEDQYPRK IIIPYPKAGAKNPTVKVFIVDTTNI EAFGPKEVPVPAVIASSDHYFTWLT WVTDSRVGVQWLKRIQNFSVLAICD FKENSNTWDCPENQQHIEESQTGWA GGFFVSAPYFTSDGSSYYKIFSDKN GYKHIHYINGSVENAIQITSGEWEA IYIFRVTNDAIFYSSNEFEGYPGRR NIYKISIGSKPIRKLCITCNLRKER CQYYTARFSERSKYYALICYGPGIP ISTLFENESDRELRILEDNQELQSA LQEIILPKEEINKLEVDGITLWYKM LIPPQFDRSKKYPLLIQVYGGPCSQ NVKHTFSISWITYLASKEGIIVALV DGRGTAYQGDKILHAVYRRLGVYEV EDQISAVKKFIEMGFIDEKRIAIWG WSYGGYVTSLALGSGSGVFKCGIAV APVSSWEYYASIYTERFMGLPVESD NLEHYKNSTVMARAKNFQNVEYLLI HGTADDNVHFQNSAQIAKALVNAQV DFQAMWYTDQNHGIPGLSSKHLYTH MTHFLKQCFSLSE
• Endotoxin: < 1 EU/μg by LAL
• Purity: > 95% by SDS-PAGE
• Storage: Store it under sterile conditions at -20 to -80 centigade. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
• Concentration: 0.38 mg/mL by BCA
• Storage Buffer: Sterile PBS, pH7.4

Gene Information

• Gene Name: FAP fibroblast activation protein alpha [ Gallus gallus (chicken) ]
• Official Symbol: FAP
• Synonyms: FAP; fibroblast activation protein alpha; prolyl endopeptidase FAP; EC 3.4.14.5; EC 3.4.21.26
• Gene ID: 424186
• mRNA Refseq: NM_001193639
• Protein Refseq: NP_001180568
• UniProt ID: A0A8V0ZGU9