Recombinant Cynomolgus CCL1 Protein, Fc Tagged

• Cat.No.: CCL1-11231C
• Product Overview: Cynomolgus CCL1 Protein, Fc Tag is expressed from human 293 cells (HEK293). It contains AA Lys 24-Lys 96 (Accession # A0A8J8Y905). This protein carries a human IgG1 Fc tag at the C-terminus. Predicted N-terminus: Lys 24

Specification

• Species: Cynomolgus
• Source: HEK293
• Tag: Fc
• Protein Length: 24-96 aa
• Description: Chemokines form a superfamily of secreted proteins involved in immunoregulatory and inflammatory processes. The superfamily is divided into four subfamilies based on the arrangement of the N-terminal cysteine residues of the mature peptide. CCL1, a member of the CC subfamily, is secreted by activated T cells and displays chemotactic activity for monocytes but not for neutrophils. It binds to the chemokine (C-C motif) receptor 8.
• Form: Lyophilized from 0.22 μm filtered solution in PBS, pH7.4 with trehalose as protectant.
• Molecular Mass: The protein has a calculated MW of 34.9 kDa. The protein migrates as 40-43 kDa when calibrated against Star Ribbon Pre-stained Protein Marker under reducing (R) condition (SDS-PAGE) due to glycosylation.
• Endotoxin: Less than 1.0 EU/μg by the LAL method/rFC method.
• Purity: >90% as determined by SDS-PAGE.
• Storage: This product is stable after storage at: -20 to -70 centigrade for 12 months in lyophilized state; -70 centigrade for 3 months under sterile conditions after reconstitution. For long term storage, the product should be stored at lyophilized state at -20 centigrade or lower. Please avoid repeated freeze-thaw cycles.
• Reconstitution: It is recommended that sterile water be added to the vial to prepare a stock solution of 0.2 μg/μL. Centrifuge the vial at 4 centigrade before opening to recover the entire contents.

Gene Information

• Gene Name: CCL1 C-C motif chemokine ligand 1 [ Macaca fascicularis (crab-eating macaque) ]
• Official Symbol: CCL1
• Synonyms: CCL1; C-C motif chemokine ligand 1; C-C motif chemokine 1; Small-inducible cytokine A1
• Gene ID: 102138189
• mRNA Refseq: XM_005583426
• Protein Refseq: XP_005583483
• UniProt ID: A0A8J8Y905